Schmitt K P, Boehm T, Fleck M, Kaiser W A
Institut für Diagnostische und Interventionelle Radiologieder Friedrich-Schiller-Universität Jena, Germany.
Rofo. 2001 Oct;173(10):898-901. doi: 10.1055/s-2001-17595.
Cost-effectiveness of MR-imaging in the preoperative work-up of suspicious breast lesions.
To assess the clinical and economic consequences of a preoperative magnetic resonance mammography (MRM) in patients with suspicious breast lesions.
483 out of 2426 patients operated because of breast neoplasms at the University Hospital of Jena between August 1995 and March 1999 underwent preoperative Gd-enhanced breast MRI in addition to mammography and breast ultrasound because of suspicious breast lesions. The histological assessment was correlated with the results of the diagnostic imaging work-up in 447 cases. The costs of surgery for malignant lesions were calculated based on case- dependent billing agreements, costs of surgery of benign lesions were calculated based on current billing procedure. In 36 cases no surgery was performed due to the exclusion of malignancy by breast MRI. 140 benign lesions were treated surgically in spite of negative breast MRI diagnosis. The hospitalization time related costs caused by these cases were compared to the costs of preoperative MR-imaging.
The total costs for MR mammography in all 483 patients amounted to DM 499,857. In 11 cases false positive results in MRM led to additional costs of DM 32,565. Assuming that there is no need for surgical treatment of benign breast lesions, total savings of DM 521,048 due to avoided hospitalization in 176 cases could have been possible. The savings per patient amount in these 176 cases are DM 2,960.50 compared to DM 1,034.90 costs for breast MRI.
Despite the currently still high costs of breast MRI a major cost reduction can be achieved by prevention of unnecessary surgery, avoidance of additional surgery and associated trauma for patients.
磁共振成像在可疑乳腺病变术前检查中的成本效益。
评估术前磁共振乳腺造影(MRM)对可疑乳腺病变患者的临床和经济影响。
1995年8月至1999年3月期间,在耶拿大学医院因乳腺肿瘤接受手术的2426例患者中,有483例因可疑乳腺病变,除接受乳腺X线摄影和乳腺超声检查外,还接受了术前钆增强乳腺MRI检查。对447例患者的组织学评估结果与诊断性影像学检查结果进行了相关性分析。恶性病变手术费用根据病例相关计费协议计算,良性病变手术费用根据现行计费程序计算。36例患者因乳腺MRI排除恶性肿瘤而未进行手术。尽管乳腺MRI诊断为阴性,但仍有140例良性病变接受了手术治疗。将这些病例导致的住院时间相关费用与术前MR成像费用进行了比较。
483例患者的MR乳腺造影总费用为499,857德国马克。11例MRM假阳性结果导致额外费用32,565德国马克。假设无需对良性乳腺病变进行手术治疗,176例患者因避免住院可节省总计521,048德国马克。这176例患者每人节省2,960.50德国马克,而乳腺MRI费用为1,034.90德国马克。
尽管目前乳腺MRI成本仍然较高,但通过预防不必要的手术、避免额外手术及相关患者创伤,可实现大幅成本降低。