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睡眠呼吸暂停综合征中的咽食管压力监测

Pharyngoesophageal pressure monitoring in sleep apnea syndrome.

作者信息

Reda M, Gibson G J, Wilson J A

机构信息

Otolaryngology-Head and Neck Surgery Department, Freeman Hospital, High Heaton, Newcastle Upon Tyne, NE7 7DN, UK.

出版信息

Otolaryngol Head Neck Surg. 2001 Oct;125(4):324-31. doi: 10.1067/mhn.2001.118076.

Abstract

OBJECTIVES

This study tests the sensitivity and the specificity of overnight pharyngoesophageal pressure measurement for identification and classification of obstructive sleep apnea (OSA).

METHODS

Fifty-nine snoring patients undergoing polysomnography were invited to have simultaneous pharyngoesophageal manometry. We used a soft silicone catheter with 4 microtip pressure sensors at different levels.

RESULTS

The apnea hypopnea indexes (AHIs) measured by the 2 methods were highly correlated (r = 0.971). Manometry was 100% sensitive and specific in excluding OSA and identifying severe OSA. It was 90% sensitive in identifying moderate OSA and 80% sensitive in identifying mild OSA.

CONCLUSION

Overnight ambulatory pharyngoesophageal manometry is a reliable tool for the exclusion of OSA and identification of severe OSA. It has additional advantages of localizing the level of obstruction and identifying the upper airway resistance syndrome and can be performed at home. It is cost-effective when compared with polysomnography and may aid in treatment selection for individual patients.

摘要

目的

本研究旨在测试夜间咽食管压力测量对阻塞性睡眠呼吸暂停(OSA)的识别和分类的敏感性和特异性。

方法

邀请59名接受多导睡眠图检查的打鼾患者同时进行咽食管测压。我们使用了一根带有4个不同水平微尖端压力传感器的软硅胶导管。

结果

两种方法测得的呼吸暂停低通气指数(AHIs)高度相关(r = 0.971)。测压在排除OSA和识别重度OSA方面的敏感性和特异性均为100%。在识别中度OSA方面敏感性为90%,在识别轻度OSA方面敏感性为80%。

结论

夜间动态咽食管测压是排除OSA和识别重度OSA的可靠工具。它具有定位阻塞水平和识别上气道阻力综合征的额外优势,并且可以在家中进行。与多导睡眠图相比,它具有成本效益,可能有助于个体患者的治疗选择。

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