Department of Otolaryngology-Head and Neck Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 100730, Beijing, China.
Eur Arch Otorhinolaryngol. 2011 Nov;268(11):1663-9. doi: 10.1007/s00405-011-1564-4. Epub 2011 Mar 30.
The aim of this study was to determine whether the 2-h daytime ApneaGraph (dAG) for patients with obstructive sleep apnea-hypopnea syndrome (OSAHS) can be used initially to diagnose and identify the site of obstruction before surgery. Fifty patients with OSAHS diagnosed by polysomnogram were enrolled in this prospective study. Sleep-related parameters, which include the indices for apnea-hypopnea (AHI), apnea index (AI), obstructive, central and mixed AHI (OAHI, CAHI and MAHI, respectively), the lowest oxygen saturation (LSaO₂) and the proportion of upper and lower airway obstruction (UPPER and LOWER, respectively), were measured by both daytime and nocturnal AG (nAG). Different operative techniques were used according to the obstruction site assessed by the nAG. Clinical outcomes were assessed with the Epworth Sleepiness Scale (ESS), visual analog scale (VAS), AI, AHI and LSaO₂. All the indices except LSaO₂ found no significant differences between dAG and nAG; there were significant positive correlations with regard to most indices, but not for CAHI between dAG and nAG. When compared dAG with nAG, most moderate and severe patients had predominant sites of obstructions in the upper level. Postoperative ESS, VAS, AI and AHI decreased significantly, while LSaO₂ significantly increased compared with those preoperative counterparts. dAG may be used as an alternative means for early and low-cost diagnostic evaluation of OSAHS before surgery.
本研究旨在确定阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者的 2 小时日间 ApneaGraph(dAG)是否可用于在手术前初步诊断和识别阻塞部位。本前瞻性研究纳入了 50 例经多导睡眠图诊断为 OSAHS 的患者。通过日间和夜间 AG(nAG)测量睡眠相关参数,包括呼吸暂停低通气指数(AHI)、呼吸暂停指数(AI)、阻塞性、中枢性和混合性 AHI(OAHI、CAHI 和 MAHI)、最低氧饱和度(LSaO₂)以及上气道和下气道阻塞的比例(UPPER 和 LOWER)。根据 nAG 评估的阻塞部位,采用不同的手术技术。采用 Epworth 嗜睡量表(ESS)、视觉模拟量表(VAS)、AI、AHI 和 LSaO₂评估临床结果。除 LSaO₂外,dAG 与 nAG 之间的所有指数均无显著差异;大多数指数之间存在显著正相关,但 dAG 与 nAG 之间的 CAHI 无显著相关性。与 nAG 相比,dAG 时大多数中度和重度患者上气道阻塞为主。与术前相比,术后 ESS、VAS、AI 和 AHI 显著降低,LSaO₂显著升高。dAG 可作为 OSAHS 术前早期、低成本诊断评估的替代手段。