Starling L M, Boullin D J, Grahame-Smith D G, Adams C B, Gye R S
J Neurol Neurosurg Psychiatry. 1975 Jul;38(7):650-6. doi: 10.1136/jnnp.38.7.650.
The isolated human basilar artery suspended in Kreb's solution contracts to 5-hydroxy-tryptamine, noradrenaline, and histamine, which stimulate specific receptors. Normal human serum contains an unidentified contractile substance, and erythrocytes relax the artery. Serum and erythrocytes potentiate 5-HT contractions. This preparation is suitable for studying vasoactive substances released during vasospasm after subarachnoid haemorrhage.
悬浮于克雷布斯溶液中的离体人基底动脉会对5-羟色胺、去甲肾上腺素和组胺产生收缩反应,这些物质会刺激特定受体。正常人血清中含有一种未明确的收缩物质,而红细胞会使动脉舒张。血清和红细胞会增强5-羟色胺引起的收缩。该制剂适用于研究蛛网膜下腔出血后血管痉挛期间释放的血管活性物质。