• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

蛛网膜下腔出血患者脑脊液中存在血管活性物质（可能与脑动脉痉挛的病因有关）的证据。

Evidence for the presence of a vasoactive substance (possibly involved in the aetiology of cerebral arterial spasm) in cerebrospinal fluid from patients with subarachnoid haemorrhage.

作者信息

Boullin D J, Mohan J, Grahame-Smith D G

出版信息

J Neurol Neurosurg Psychiatry. 1976 Aug;39(8):756-66. doi: 10.1136/jnnp.39.8.756.

DOI:10.1136/jnnp.39.8.756
PMID:956862
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC492444/
Abstract

Cerebrospinal fluid from patients with subarachnoid haemorrhage and cerebral arterial spasm contracted the isolated basilar artery and potentiated contractions produced by 5-hydroxytryptamine, noradrenaline, and six prostaglandins. The unidentified substance in cerebrospinal fluid probably plays a role in the aetiology of cerebral arterial spasm.

摘要

蛛网膜下腔出血和脑动脉痉挛患者的脑脊液可使离体的基底动脉收缩，并增强5-羟色胺、去甲肾上腺素和六种前列腺素所引起的收缩。脑脊液中这种未明确的物质可能在脑动脉痉挛的病因学中起作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/033c/492444/fcd825f12f70/jnnpsyc00170-0042-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/033c/492444/fcd825f12f70/jnnpsyc00170-0042-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/033c/492444/fcd825f12f70/jnnpsyc00170-0042-a.jpg

相似文献

1
Evidence for the presence of a vasoactive substance (possibly involved in the aetiology of cerebral arterial spasm) in cerebrospinal fluid from patients with subarachnoid haemorrhage.蛛网膜下腔出血患者脑脊液中存在血管活性物质（可能与脑动脉痉挛的病因有关）的证据。
J Neurol Neurosurg Psychiatry. 1976 Aug;39(8):756-66. doi: 10.1136/jnnp.39.8.756.
2
Cerebral arterial spasm. 2. In vitro contractile activity of serotonin in human serum and CSF on the canine basilar artery, and its blockage by methylsergide and phenoxybenzamine.1. 脑动脉痉挛。2. 人血清和脑脊液中5-羟色胺对犬基底动脉的体外收缩活性及其被甲基麦角新碱和酚苄明阻断的情况。
J Neurosurg. 1974 Apr;40(4):442-50. doi: 10.3171/jns.1974.40.4.0442.
3
Responses of isolated human basilar arteries to 5-hydroxytryptamine, noradrenaline, serum, platelets, and erythrocytes.离体人基底动脉对5-羟色胺、去甲肾上腺素、血清、血小板和红细胞的反应。
J Neurol Neurosurg Psychiatry. 1975 Jul;38(7):650-6. doi: 10.1136/jnnp.38.7.650.
4
Cerebral arterial spasm. Part 5: in vitro contractile activity of vasoactive agents including human CSF on human basilar and anterior cerebral arteries.脑动脉痉挛。第5部分：包括人脑脊液在内的血管活性药物对人基底动脉和大脑前动脉的体外收缩活性
J Neurosurg. 1976 May;44(5):594-600. doi: 10.3171/jns.1976.44.5.0594.
5
Relationship between presence of vasoconstrictor activity in cerebrospinal fluid and time after subarachnoid haemorrhage from rupture of cerebral arterial aneurysms.脑动脉动脉瘤破裂导致蛛网膜下腔出血后，脑脊液中血管收缩活性的存在与时间的关系。
J Neurol Neurosurg Psychiatry. 1979 Jul;42(7):625-34. doi: 10.1136/jnnp.42.7.625.
6
Effects of (+) and (-)-propranolol on the responses of the human isolated basilar artery to cerebrospinal fluid obtained from patients with subarachnoid haemorrhage and cerebral arterial spasm.（+）和（-）-普萘洛尔对人离体基底动脉对蛛网膜下腔出血和脑动脉痉挛患者脑脊液反应的影响。
Br J Clin Pharmacol. 1977 Feb;4(1):27-31. doi: 10.1111/j.1365-2125.1977.tb00662.x.
7
Cerebral arterial spasm. 1. In vitro contractile activity of vasoactive agents on canine basilar and middle cerebral arteries.脑动脉痉挛。1. 血管活性药物对犬基底动脉和大脑中动脉的体外收缩活性。
J Neurosurg. 1974 Apr;40(4):433-41. doi: 10.3171/jns.1974.40.4.0433.
8
Individual variations in response of human cerebral arterioles to vasoactive substances, human plasma, and CSF from patients with aneurysmal SAH.人脑小动脉对血管活性物质、人血浆和动脉瘤性蛛网膜下腔出血患者脑脊液反应的个体差异。
J Neurosurg. 1981 Sep;55(3):431-7. doi: 10.3171/jns.1981.55.3.0431.
9
[Changes in 5-hydroxyindoleacetic acid (5-HIAA) in the cerebrospinal fluid after subarachnoid hemorrhage in relation to the clinical data and arterial spasm].蛛网膜下腔出血后脑脊液中5-羟吲哚乙酸（5-HIAA）的变化与临床资料及动脉痉挛的关系
Riv Neurobiol. 1977 Oct-Dec;23(4):219-28.
10
[Fibrinolytic activity of cerebrospinal fluid as an indicator of the risk of repeated ruptures of arterial aneurysms].[脑脊液纤维蛋白溶解活性作为动脉性动脉瘤再次破裂风险的指标]
Zh Vopr Neirokhir Im N N Burdenko. 1985 Jul-Aug(4):18-22.

引用本文的文献

1
Bilirubin Oxidation Products and Cerebral Vasoconstriction.胆红素氧化产物与脑血管收缩
Front Pharmacol. 2018 Apr 27;9:303. doi: 10.3389/fphar.2018.00303. eCollection 2018.
2
Spinal trauma: pharmacological evidence for vasoconstrictor activity in cerebrospinal fluid.脊柱创伤：脑脊液中血管收缩活性的药理学证据
J Neurol Neurosurg Psychiatry. 1981 Aug;44(8):725-7. doi: 10.1136/jnnp.44.8.725.
3
The calibre of cerebral arteries of the rat studied by carotid angiography: a model system for studying the aetiology of human cerebral arterial constriction after aneurysmal rupture.

本文引用的文献

1
DEMONSTRATION OF SUBSTANCES CAPABLE OF CONTRACTING SMOOTH MUSCLE IN THE HAEMATOMA FLUID FROM CERTAIN CASES OF RUPTURED CEREBRAL ANEURYSM.某些破裂脑动脉瘤病例血肿液中能使平滑肌收缩的物质的证明。
J Neurol Neurosurg Psychiatry. 1964 Jun;27(3):198-9. doi: 10.1136/jnnp.27.3.198.
2
EFFECT OF VARIOUS PHARMACOLOGIC AGENTS ON CEREBRAL ARTERIES.各种药理制剂对脑动脉的作用
Neurology. 1963 Sep;13:772-8. doi: 10.1212/wnl.13.9.772.
3
Cerebrovascular effects of topically applied serotonin in the cat.局部应用血清素对猫脑血管的影响。
通过颈动脉血管造影术研究大鼠脑动脉的管径：一种用于研究动脉瘤破裂后人类脑动脉狭窄病因的模型系统。
Neuroradiology. 1981;21(5):245-52. doi: 10.1007/BF02100154.
4
The pathophysiology of cerebral vasospasm, and pharmacological approaches to its management.脑血管痉挛的病理生理学及其治疗的药理学方法。
Acta Neurochir (Wien). 1982;63(1-4):253-8. doi: 10.1007/BF01728879.
5
Effect of leucotrienes C4, D4, prostacyclin and thromboxane A2 on isolated human cerebral arteries.白三烯C4、D4、前列环素和血栓素A2对离体人脑动脉的作用。
Acta Neurochir (Wien). 1982;62(3-4):177-85. doi: 10.1007/BF01403622.
6
Prediction of cerebral vasospasm value of fibrinogen degradation products (FDP) in the cerebro-spinal fluid (CSF) for prediction of vasospasm following subarachnoid haemorrhage due to a ruptured aneurysm.预测脑脊液（CSF）中纤维蛋白原降解产物（FDP）对破裂动脉瘤所致蛛网膜下腔出血后血管痉挛的预测价值。
Acta Neurochir (Wien). 1984;73(1-2):25-33. doi: 10.1007/BF01401781.
7
The 5-hydroxytryptamine antagonist ketanserin inhibits the vasoconstrictor activity of per-operative CSF, from subarachnoid haemorrhage patients, on isolated tissues.5-羟色胺拮抗剂酮色林可抑制蛛网膜下腔出血患者术中脑脊液对离体组织的血管收缩活性。
J Neurol Neurosurg Psychiatry. 1983 Mar;46(3):214-20. doi: 10.1136/jnnp.46.3.214.
8
The pathogenetic and prognostic significance of blood-brain barrier damage at the acute stage of aneurysmal subarachnoid haemorrhage. Clinical and experimental studies.动脉瘤性蛛网膜下腔出血急性期血脑屏障损伤的发病机制及预后意义。临床与实验研究。
Acta Neurochir (Wien). 1985;77(3-4):110-32. doi: 10.1007/BF01476215.
9
Serotonin and the vascular system. Role in health and disease, and implications for therapy.血清素与血管系统。在健康和疾病中的作用以及对治疗的意义。
Drugs. 1986 Feb;31(2):149-63. doi: 10.2165/00003495-198631020-00004.
10
Effect of intracisternal thromboxane A2 analogue on cerebral artery permeability.脑池内血栓素A2类似物对脑动脉通透性的影响。
Acta Neurochir (Wien). 1988;90(3-4):144-51. doi: 10.1007/BF01560570.
Neurology. 1961 Mar;11:190-5. doi: 10.1212/wnl.11.3.190.
4
The spontaneous release of prostaglandins into the cerebral ventricles of the dog and the effect of external factors on this release.前列腺素在犬脑室中的自发释放以及外部因素对这种释放的影响。
Br J Pharmacol. 1970 Apr;38(4):653-8. doi: 10.1111/j.1476-5381.1970.tb09874.x.
5
Autonomous activity in the human basilar artery: relationship to cerebral vascular spasm.人基底动脉的自主活动：与脑血管痉挛的关系
Neurology. 1971 Dec;21(12):1249-54. doi: 10.1212/wnl.21.12.1249.
6
Experimental vasoconstriction of cerebral arteries by prostaglandins.前列腺素对脑动脉的实验性血管收缩作用。
J Neurosurg. 1972 Oct;37(4):385-97. doi: 10.3171/jns.1972.37.4.0385.
7
Current concepts in the etiology and treatment of vasospasm.血管痉挛病因及治疗的当前概念
Clin Neurosurg. 1968;15:133-60. doi: 10.1093/neurosurgery/15.cn_suppl_1.133.
8
Experimental vasospasm, acute and chronic, due to blood in the subarachnoid space.实验性血管痉挛，急性和慢性，由蛛网膜下腔出血引起。
J Neurosurg. 1971 Dec;35(6):646-56. doi: 10.3171/jns.1971.35.6.0646.
9
Cerebral arterial spasm. 2. In vitro contractile activity of serotonin in human serum and CSF on the canine basilar artery, and its blockage by methylsergide and phenoxybenzamine.1. 脑动脉痉挛。2. 人血清和脑脊液中5-羟色胺对犬基底动脉的体外收缩活性及其被甲基麦角新碱和酚苄明阻断的情况。
J Neurosurg. 1974 Apr;40(4):442-50. doi: 10.3171/jns.1974.40.4.0442.
10
Effects of prostaglandins E 1 , E 2 , A 1 , A 2 , and F 2 on canine carotid arterial blood flow, cerebrospinal fluid pressure, and intraocular pressure.前列腺素E1、E2、A1、A2和F2对犬颈动脉血流量、脑脊液压力和眼压的影响。
J Neurosurg. 1973 Jan;38(1):32-9. doi: 10.3171/jns.1973.38.1.0032.