Frates E P, Burke D T, Chae H, Ahangar B
Spaulding Rehabilitation Hospital, Harvard Medical School, Boston, MA 02114, USA.
Brain Inj. 2001 Oct;15(10):911-6. doi: 10.1080/02699050110063468.
Previous reports in the literature concerning cerebrovascular accident have illustrated cases of post-stroke tremor. Treatments of these studies have varied. Trials of levo-dopa have been reported in two such cases. This case study reports on a case of a patient with a left thalamic, left superior cerebellar artery infarction with a lacunar infarction in the basal ganglia. The patient developed a violent tremor/movement disorder which was unresponsive to haloperidol. With this failure, and with the evidence of a basal ganglion lesion, levo-dopa/carbi-dopa was introduced as an intervention. The amplitude of the tremor was dramatically reduced, with protective devices removed, and with complete cessation of the tremor at rest. The medication was withdrawn and reintroduced with a reduction and subsequent resolution of the symptoms. A discussion of the previous studies of movement disorder with cerebrovascular accident is included.
文献中先前有关脑血管意外的报告已经阐述了中风后震颤的病例。这些研究的治疗方法各不相同。在两例此类病例中报告了左旋多巴试验。本病例研究报告了一名患有左侧丘脑、左侧小脑上动脉梗死并伴有基底节腔隙性梗死的患者。该患者出现了剧烈震颤/运动障碍，对氟哌啶醇无反应。由于这种治疗失败，且有基底节病变的证据，于是引入左旋多巴/卡比多巴作为干预措施。震颤幅度显著降低，防护装置被移除，静息时震颤完全停止。药物停用后重新使用，症状减轻并随后消失。文中还包括了先前关于脑血管意外导致运动障碍的研究讨论。
