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[炮制方法对马钱子生物碱、毒性及药效的影响]

[Influence of processing methods on alkaloid, toxicity and effect of Strychnos nux-vomica L].

作者信息

Chen X, Gui X, Xie Z

机构信息

Fujian Institute of Traditional Chinese Medicine and Pharmacology, Fuzhou 350003.

出版信息

Zhongguo Zhong Yao Za Zhi. 1998 Mar;23(3):151-3, 191.

Abstract

Determination has been made on the contents of strychnine, brucine and ephedrin in different processed products of Strychnos nux-vomica. The acute toxicity, analgesic and antiphlogistic actions of these products have also been detected. The result shows that the product processed with Ephedra sinica can reduce toxicity and promote curative effect. Among the different processing methods the preparation with Ephedra and Liqorice root and the preparation with Ephedra and alcohol appear better and thus useful in practical application.

摘要

已对马钱子不同炮制品中士的宁、马钱子碱和麻黄碱的含量进行了测定。还检测了这些制品的急性毒性、镇痛和抗炎作用。结果表明,用麻黄炮制的制品可降低毒性并提高疗效。在不同的炮制方法中,麻黄甘草制和麻黄酒制较好,可用于实际应用。

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