Wang F S, Cai H, Yang J S, Zhang Y M, Hou C Y, Liu J Q, Zhao M J
Department of Chemistry, University of Agriculture and Animal Science, PLA, Chang Chun 130062.
Yao Xue Xue Bao. 1997 Jun;32(6):447-50.
Three compounds have been isolated from the dichloromethane soluble fraction of the fruiting body of Ganoderma lucidum (Fr.) Karst. On basis of spectral analyses (UV, IR, MS, 1HNMR, 13CNMR and 2D-NMR), they were identified as 3, 7-dioxo-lanosta-8, 24(E)-dien-26-oic acid (I), 7 beta-15 alpha-dihydroxy-3, 11, 23-trioxo-5 alpha-lanost-8-en-26-oic acid (II) and 3 beta, 7 beta, 15 alpha-trihydroxy-11, 23-dioxo-5 alpha-lanosta-8-en-26-oic acid (III). Compound I is a new compound named ganoderic acid DM.
从灵芝(Fr.)Karst.子实体的二氯甲烷可溶部分中分离出三种化合物。根据光谱分析(紫外、红外、质谱、1H核磁共振、13C核磁共振和二维核磁共振),它们被鉴定为3,7-二氧代-羊毛甾-8,24(E)-二烯-26-酸(I)、7β-15α-二羟基-3,11,23-三氧代-5α-羊毛甾-8-烯-26-酸(II)和3β,7β,15α-三羟基-11,23-二氧代-5α-羊毛甾-8-烯-26-酸(III)。化合物I是一种新化合物,命名为灵芝酸DM。