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[灵芝孢子中三萜类成分的研究]

[Studies on the triterpenoid constituents of the spores from Ganoderma lucidum karst].

作者信息

Chen R Y, Yu D Q

机构信息

Institute of Materia Medica, Chinese Academy of Medical Sciences, Beijing.

出版信息

Yao Xue Xue Bao. 1991;26(4):267-73.

PMID:1957672
Abstract

Five compounds were isolated from the ether soluble fraction of the spores of Ganoderma lucidum. On the basis of their chemical properties and spectral data (MS, UV, IR, 1H and 13CNMR), they were identified as 3,7,11,12,15,23-hexaoxo-5 alpha-lanosta-8-en-26-oic acid (I), 3 beta,7 beta-dihydroxy-11,15,23-trioxo-5 alpha-lanosta-8-en-26-oic acid (II), 7 beta-hydroxy-3,11,15,23-tetraoxo-5 alpha-lanosta-8-en-26-oic acid (III), 3,7,11,15,23-pentaoxo-5 alpha-lanosta-8-en-26-oic acid (IV), 24,25,26-trihydroxy-5 alpha-lanosta-7,9 (11)-dien-3-one (V), Compound I is a new natural product, named ganosporeric acid A. Compounds II, III, IV and V were obtained for the first time from the spores of Ganoderma lucidum.

摘要

从灵芝孢子的乙醚可溶部分分离出了五种化合物。根据它们的化学性质和光谱数据(质谱、紫外光谱、红外光谱、氢核磁共振和碳核磁共振),它们被鉴定为3,7,11,12,15,23 - 六氧代 - 5α - 羊毛甾 - 8 - 烯 - 26 - 酸(I)、3β,7β - 二羟基 - 11,15,23 - 三氧代 - 5α - 羊毛甾 - 8 - 烯 - 26 - 酸(II)、7β - 羟基 - 3,11,15,23 - 四氧代 - 5α - 羊毛甾 - 8 - 烯 - 26 - 酸(III)、3,7,11,15,23 - 五氧代 - 5α - 羊毛甾 - 8 - 烯 - 26 - 酸(IV)、24,25,26 - 三羟基 - 5α - 羊毛甾 - 7,9(11) - 二烯 - 3 - 酮(V)。化合物I是一种新的天然产物,命名为灵芝孢子酸A。化合物II、III、IV和V首次从灵芝孢子中获得。

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