在整个随访过程中，一名柯萨科夫综合征患者的非典型神经心理学特征。

An atypical neuropsychological profile of a Korsakoff syndrome patient throughout the follow-up.

作者信息

Noël X, Schmidt N, Van der Linden M, Sferrazza R, Hanak C, De Mol J, Kornreich C, Pelc I, Verbanck P

机构信息

Department of Psychiatry, Free University of Brussels, Brugmann Hospital, Brussels, Belgium.

出版信息

Eur Neurol. 2001;46(3):140-7. doi: 10.1159/000050787.

DOI:10.1159/000050787

PMID:11598332

Abstract

The basis of amnesia in alcoholic Wernicke-Korsakoff syndrome (WKS) has been generally associated with diencephalic lesions and more specifically with lesions of the anterior thalamic nuclei. These brain structures are considered to be involved in encoding/consolidation processes of episodic memory. However, frontal lobe damage responsible for executive function deficits has also been documented. The present report details the nature and extent of amnesia in an alcoholic patients with WKS and which appears to be mainly due to frontal lobe (executive) deficits.

摘要

酒精性韦尼克-科尔萨科夫综合征（WKS）所致失忆的基础通常与间脑病变有关，更具体地说是与丘脑前核的病变有关。这些脑结构被认为参与情景记忆的编码/巩固过程。然而，负责执行功能缺陷的额叶损伤也有文献记载。本报告详细阐述了一名患有WKS的酒精性患者失忆的性质和程度，而这种失忆似乎主要是由额叶（执行）功能缺陷所致。