Parkin A J, Dunn J C, Lee C, O'Hara P F, Nussbaum L
University of Sussex, Brighton, England.
Brain Cogn. 1993 Jan;21(1):1-19. doi: 10.1006/brcg.1993.1001.
This article reports the neuropsychological sequelae of Wernicke's Encephalopathy in a 20-year-old woman. After amelioration of acute symptoms, the patient showed a range of cognitive impairments the most marked of which was a severe impairment on free recall tasks involving both verbal and nonverbal material. In contrast, recognition memory appeared remarkably well preserved. Some evidence of frontal lobe and general intellectual impairment was also noted. The case is discussed in terms of the pathophysiology of Wernicke-Korsakoff Syndrome, criteria for its diagnosis, and the multicomponent nature of memory deficits.
本文报道了一名20岁女性韦尼克脑病的神经心理学后遗症。急性症状缓解后，患者表现出一系列认知障碍，其中最明显的是在涉及言语和非言语材料的自由回忆任务上存在严重障碍。相比之下，识别记忆似乎保存得非常好。还发现了一些额叶和一般智力受损的证据。本文从韦尼克-科尔萨科夫综合征的病理生理学、诊断标准以及记忆缺陷的多成分性质等方面对该病例进行了讨论。
