Kim W Y, Stuber M, Kissinger K V, Andersen N T, Manning W J, Botnar R M
Department of Medicine (Cardiovascular Division), Beth Israel Deaconess Medical Center and Harvard Medical School, 330 Brookline Ave., Boston, MA 02215, USA.
J Magn Reson Imaging. 2001 Oct;14(4):383-90. doi: 10.1002/jmri.1198.
The purpose of this study was to investigate the impact of in-plane coronary artery motion on coronary magnetic resonance angiography (MRA) and coronary MR vessel wall imaging. Free-breathing, navigator-gated, 3D-segmented k-space turbo field echo ((TFE)/echo-planar imaging (EPI)) coronary MRA and 2D fast spin-echo coronary vessel wall imaging of the right coronary artery (RCA) were performed in 15 healthy adult subjects. Images were acquired at two different diastolic time periods in each subject: 1) during a subject-specific diastasis period (in-plane velocity <4 cm/second) identified from analysis of in-plane coronary artery motion, and 2) using a diastolic trigger delay based on a previously implemented heart-rate-dependent empirical formula. RCA vessel wall imaging was only feasible with subject-specific middiastolic acquisition, while the coronary wall could not be identified with the heart-rate-dependent formula. For coronary MRA, RCA border definition was improved by 13% (P < 0.001) with the use of subject-specific trigger delay (vs. heart-rate-dependent delay). Subject-specific middiastolic image acquisition improves 3D TFE/EPI coronary MRA, and is critical for RCA vessel wall imaging.
本研究的目的是调查平面内冠状动脉运动对冠状动脉磁共振血管造影(MRA)和冠状动脉磁共振血管壁成像的影响。对15名健康成年受试者进行了自由呼吸、导航门控、三维分段k空间涡轮场回波((TFE)/回波平面成像(EPI))冠状动脉MRA以及右冠状动脉(RCA)的二维快速自旋回波冠状动脉血管壁成像。在每个受试者的两个不同舒张期采集图像:1)在通过分析平面内冠状动脉运动确定的受试者特定舒张中期(平面内速度<4厘米/秒)期间,以及2)使用基于先前实施的心率相关经验公式的舒张期触发延迟。RCA血管壁成像仅在受试者特定的舒张中期采集时可行,而使用心率相关公式无法识别冠状动脉壁。对于冠状动脉MRA,使用受试者特定的触发延迟(相对于心率相关延迟)时,RCA边界定义改善了13%(P<0.001)。受试者特定的舒张中期图像采集改善了三维TFE/EPI冠状动脉MRA,并且对于RCA血管壁成像至关重要。