Anton G, Achim R, Pleşa A, Repanovici R
Stefan S. Nicolau Institute of Virology, Bucharest.
Rom J Virol. 1999 Jan-Dec;50(1-4):91-7.
Infection with human papillomavirus (HPV) has been established to be a sexually transmitted disease, with a potential risk of intraepithelial neoplasia and invasive cancer, function of the genotype involved. Scraped cells from lesions of 27 men establishing various types of penile warts were investigated by PCR for HPV DNA detection. Twenty patients (76.9%) were found to have an HPV infection. By RFLP genotyping of only 13 samples, 4 HPV16. 2 HPV6 and 7 HPV ND infections were determined. Comments about these cases, in correlation with other factors are presented. The findings in this study confirmed the HPV involvement in penile warts.
人乳头瘤病毒(HPV)感染已被确认为一种性传播疾病,根据所涉及的基因型不同,存在上皮内瘤变和浸润性癌的潜在风险。通过聚合酶链反应(PCR)对27例患有各种类型阴茎疣的男性病变部位刮取的细胞进行检测,以确定HPV DNA。结果发现20例患者(76.9%)存在HPV感染。仅对13个样本进行限制性片段长度多态性(RFLP)基因分型,确定有4例HPV16感染、2例HPV6感染和7例HPV未定型感染。本文结合其他因素对这些病例进行了讨论。本研究结果证实了HPV与阴茎疣有关。