Cordina M, McElnay J C, Hughes C M
Department of Pharmacy, University of Malta, Msida.
Pharmacotherapy. 2001 Oct;21(10):1196-203. doi: 10.1592/phco.21.15.1196.33894.
To implement and assess a community-based pharmaceutical care program for patients with asthma.
Prospective, randomized, controlled trial.
Community pharmacies (11 control, 11 intervention) in Malta.
Community-dwelling patients with asthma.
A comprehensive asthma education and monitoring program was implemented. Intervention patients received verbal counseling, an educational video, an information leaflet, and subsequent monitoring with reinforcement; control patients received routine dispensing services.
Parameters assessed at baseline and at 4, 8, and 12 months were health-related quality of life, peak expiratory flow (PEF), inhaler technique, compliance with therapy, hospitalization rates, days lost from work, asthma symptoms, and patient satisfaction. Health-related quality of life of the intervention patients improved at 12 months (p=0.044). In the same time period, PEF significantly decreased in control patients compared with intervention patients (p=0.009) whereas inhaler technique improved in the intervention group (p=0.021). There were significantly fewer self-reported hospitalizations in intervention patients.
A community-based pharmaceutical care program was appreciated by the participants and had a positive impact on the vitality of patients with asthma, inhaler technique, and PEE.
为哮喘患者实施并评估一项基于社区的药学服务项目。
前瞻性、随机、对照试验。
马耳他的社区药房（11家对照，11家干预）。
社区居住的哮喘患者。
实施一项全面的哮喘教育与监测项目。干预组患者接受口头咨询、一部教育视频、一份信息传单以及后续强化监测；对照组患者接受常规配药服务。
在基线以及第4、8和12个月评估的参数包括健康相关生活质量、呼气峰值流速（PEF）、吸入器使用技术、治疗依从性、住院率、误工天数、哮喘症状以及患者满意度。干预组患者的健康相关生活质量在12个月时有所改善（p = 0.044）。在同一时期，与干预组患者相比，对照组患者的PEF显著下降（p = 0.009），而干预组的吸入器使用技术有所改善（p = 0.021）。干预组患者自我报告的住院次数明显较少。
基于社区的药学服务项目受到参与者的认可，对哮喘患者的活力、吸入器使用技术和呼气峰值流速有积极影响。
