Roland M, Leisten D, Kane R
Obstet Gynecol. 1975 Sep;46(3):308-10.
In a continuing oral contraceptive study of d-norgestrel, the 1,0-mg dose--the dose previously found to give the best cycle control--was administered cyclically on a "21-7 day" schedule to 284 women during 2650 cycles. None of the women conceived, and cycle control, though often altered, was generally acceptable. Side effects were minimal, and laboratory determinations performed prior to and during the administration of this agent revealed no clinically significant changes.
在一项关于炔诺孕酮的复方口服避孕药研究中，采用“21天服药-7天停药”的方案，将先前发现能实现最佳周期控制的1.0毫克剂量的炔诺孕酮周期性地给予284名女性，共进行了2650个周期。所有女性均未怀孕，周期控制虽常有所改变，但总体上是可接受的。副作用极小，在服用该药物之前及服药期间进行的实验室检测未发现具有临床意义的变化。
