Feinstein R, Gooden B A, Wolf S
Pavlov J Biol Sci. 1975 Apr-Jun;10(2):102-11. doi: 10.1007/BF03001154.
Repeated EEG and ECG monitoring during sleep was carried out in two subjects with ischemic heart disease and one presumably healthy control. All three displayed frequent ectopic heart beats. Two had ventricular and the third atrial premature beats. The study had two objectives: (1) to ascertain the distribution of ectopic beats among the stages of sleep; and (2) to ascertain the effect of alcohol and barbiturates on the frequency of premature beats. Both drugs are known to alter the pattern of sleep stages. It was found that neither atrial nor ventricular premature beats favored a particular sleep stage. Neither drug had a consistent effect on their frequency and there was no correlation with heart rate. For the most part premature beats were fewer on the second night of a procedure although a day filled with anxiety appeared to greatly increase the frequency of premature contractions.
对两名缺血性心脏病患者和一名推测健康的对照者进行了睡眠期间的重复脑电图（EEG）和心电图（ECG）监测。三人都频繁出现异位心律。其中两人出现室性早搏，第三人出现房性早搏。该研究有两个目的：（1）确定睡眠各阶段异位心律的分布情况；（2）确定酒精和巴比妥类药物对早搏频率的影响。已知这两种药物都会改变睡眠阶段模式。结果发现，房性和室性早搏均不倾向于特定的睡眠阶段。两种药物对早搏频率均无一致影响，且与心率无关。在操作的第二晚，早搏大多减少，不过充满焦虑的一天似乎会大幅增加早搏频率。
