Borg J, Gershon S, Alpert M
Psychopharmacologia. 1975 Jun 19;42(3):211-8. doi: 10.1007/BF00421258.
Graded doses of marihuana were administered to five adults in a longitudinal repeated-measurements design. Speed of response was the basic parameter measured accross tests of increasing cognitive involvement. Marihuana produced significant dose-response effects of impaired performance in all test scores. However, single automatic motor abilities demonstrated greater sensitivity than tests of greater complexity. Evidence is presented for tolerance development.
采用纵向重复测量设计，对五名成年人施用不同剂量的大麻。反应速度是在越来越复杂的认知参与测试中测量的基本参数。大麻在所有测试分数中均产生了显著的剂量反应效应，即表现受损。然而，单一的自动运动能力比更复杂的测试表现出更高的敏感性。文中提供了耐受性发展的证据。
