The effects of Cannabis sativa on the behavior of adult female chacma baboons (Papio ursinus) in captivity.

Indices of locomotory and social activity were quantified during 102 h of daily tests with two pairs of baboons under three conditions: baseline, cannabis administration, and postdrug withdrawal. Six percent of whole dried plants of cannabis (33 g) was incorporated into the daily feed. In one pair, social activity increased during cannabis administration, with no clear effect on locomotory behavior. In the second pair locomotory activity decreased, but there was no consistent change in social interaction. Thus individuals responded differently to the drug, and the social environment of each pair appeared to be implicated as a determining factor.