Pernow B
Sven Med Tidskr. 1997;1(1):147-68.
Among all the Nobel Laureates in physiology or medicine there are five from Denmark and seven from Sweden. The first three Laureates are presented in this paper. Over 50 years have elapsed since they were awarded and the Nobel archives are now open for scrutiny, providing insight into how the Nobel committee interpreted the instruction given in Nobel's will at that time. Niels Finsen (1860-1904, Nobel Laureate 1903) devoted his short life to a continuous study of the biological effects of sunshine, which resulted in a method aimed at utilizing the bacteriocide properties of sun rays in the treatment of various skin diseases and especially tuberculosis. Finsen published his first paper on this topic in 1896 and his method revolutionized the current treatment of this disease. Approximately forty Finsen Institutes were established in Europe and the USA within the subsequent five years. Alvar Gullstrand (1869-1930, Nobel Laureate 1911) was an ophthalmologist but his main interest was mathematical physics, where he achieved results of utmost importance for clinical opthalmology. He systematically studied the optical system, from the physical properties of light rays to optimal images in different media of the eye. He formulated general laws if image, which he extrapolated to the human eye. He also devised several techniques, some of which still used in ophthalmology. August Krogh (1874-1949, Nobel Laureate 1920) was a zoological physiologist, actively involved in various fields, including human muscle physiology and metabolism, capillary circulation in the frog, water regulation in the desert rat and the jumping capacity of the grasshopper. He was the founder of modern human exercise physiology and sport medicine. Krogh received the Nobel prize the year after he published his first paper on the regulation of the motor activity of capillaries, which reflected the Nobel committee's desire at that time to support a young scientist in the most successul period of his career. Through his continuous brilliant research during three decades Krogh eminently demonstrated that the committee had indeed use far-sighted judgement.
在所有诺贝尔生理学或医学奖得主中,有五位来自丹麦,七位来自瑞典。本文介绍了前三位获奖者。自他们获奖以来已过去50多年,诺贝尔档案现已开放供审查,这让我们得以了解诺贝尔委员会当时是如何解读诺贝尔遗嘱中的指示的。尼尔斯·芬森(1860 - 1904,1903年诺贝尔 laureate)将他短暂的一生奉献给了对阳光生物效应的持续研究,这促成了一种利用阳光杀菌特性治疗各种皮肤病尤其是结核病的方法。芬森于1896年发表了关于这个主题的第一篇论文,他的方法彻底改变了当时这种疾病的治疗方式。在随后的五年里,欧洲和美国大约建立了40所芬森研究所。阿尔瓦·古尔斯特兰德(1869 - 1930,1911年诺贝尔 laureate)是一位眼科医生,但他的主要兴趣是数学物理学,在这方面他取得了对临床眼科极为重要的成果。他系统地研究了光学系统,从光线的物理特性到眼睛不同介质中的最佳图像。他制定了图像的一般规律,并将其推广到人类眼睛。他还设计了几种技术,其中一些至今仍在眼科中使用。奥古斯特·克罗(1874 - 1949,1920年诺贝尔 laureate)是一位动物生理学学家,积极涉足多个领域,包括人类肌肉生理学和新陈代谢、青蛙的毛细血管循环、沙漠大鼠的水分调节以及蚱蜢的跳跃能力。他是现代人类运动生理学和运动医学的奠基人。克罗在发表关于毛细血管运动活动调节的第一篇论文后的第二年获得了诺贝尔奖,这反映了当时诺贝尔委员会希望在一位年轻科学家职业生涯最成功的时期给予支持。通过他三十年持续卓越的研究,克罗出色地证明了委员会确实具有远见卓识。