Grodnitskaia N A, Dreĭzin R S, Etkind G V, Bektemirov T A
Vopr Virusol. 1975 May-Jun(3):305-9.
Respiratory syncytial virus multiplying activity in the lungs of newborn and 6-day-old cotton rats, induced production of considerable amounts of interferon. Interferon production correlated with virus multiplication. Lower interferon titers were observed in the lungs of newborn cotton rats than in the lungs of 6-day-old animals. RS virus also induced production of serum interferon upon intraperitoneal inoculation, its titers being 2 times as low as after inoculation of equal doses of Newcastle disease virus. Poly I: poly C was shown to be a quite active interferon inducer in cotton rats and to inhibit RS virus reproduction in their lungs.
呼吸道合胞病毒在新生和6日龄棉鼠肺中的增殖活性诱导产生了大量干扰素。干扰素的产生与病毒增殖相关。在新生棉鼠的肺中观察到的干扰素滴度低于6日龄动物肺中的滴度。呼吸道合胞病毒经腹腔接种后也诱导血清干扰素的产生，其滴度是接种等量新城疫病毒后滴度的两倍。聚肌苷酸：聚胞苷酸在棉鼠中被证明是一种相当活跃的干扰素诱导剂，并能抑制其肺中呼吸道合胞病毒的繁殖。
