Sammour M B, El-Kabarity H, Khalifa A S
Acta Obstet Gynecol Scand. 1975;54(3):195-202. doi: 10.3109/00016347509157760.
Progesterone was the principal therapeutic agent used in 40 cases of pre-eclamptic toxaemia. It was also given to 10 normal pregnant women who served as a control group. A significant fall in both the systolic and diastolic blood pressures was observed in 80% of the toxaemic patients. In all cases there was a marked increase in the 24-hour urinary output with an apparent loss of weight. Serum uric acid showed a significant drop and the urea clearance values also improved. The serum sodium showed an apparent decline while the serum potassium did not show any marked variation. The serum uric acid, urea clearance, blood urea, serum sodium and serum potassium remained unchanged in the control group.
黄体酮是用于40例先兆子痫患者的主要治疗药物。它也被给予10名正常孕妇作为对照组。80%的子痫患者收缩压和舒张压均显著下降。所有病例24小时尿量均显著增加，体重明显减轻。血清尿酸显著下降，尿素清除率值也有所改善。血清钠明显下降，而血清钾无明显变化。对照组的血清尿酸、尿素清除率、血尿素、血清钠和血清钾均无变化。
