Mody M R
Am Heart J. 1975 Sep;90(3):317-21. doi: 10.1016/0002-8703(75)90319-1.
Sixty-eight patients with isolated valvular pulmonic stenosis with intact ventricular septum diagnosed by cardiac catheterization underwent a repeat study one to twelve years later which documented the progression of the lesion. These 68 patients were classified into two groups according to age. Group I comprised 37 patients who were less than one year of age at the initial study, and Group II comprised 31 patients who were older than one year of age at the time of the initial study. These 68 patients were divided into three groups according to their systolic right ventricular pressure and classified as mild, moderate, or severe. Increasing severity of the lesion was noted much more frequently in Group I, even with patients who were noted to have mild stenosis at initial cardiac catheterization. This was not as marked in Group II. The incidence of patent foramen ovale was noted to be much higher in Group I as compared with Group II. A much greater number of patients required surgery after repeat cardiac catheterization in Group I as compared with Group II. Our data indicate that mild cases of pulmonic stenosis in Group I can become severe at a later date, whereas this was less likely in Group II. Those with moderate and severe stenosis can remain the same or become more severe as age advances in both groups.
68例经心导管检查诊断为单纯性室间隔完整的肺动脉瓣狭窄患者，在1至12年后进行了重复检查，记录了病变的进展情况。根据年龄将这68例患者分为两组。第一组包括37例在初次检查时年龄小于1岁的患者，第二组包括31例在初次检查时年龄大于1岁的患者。根据收缩期右心室压力将这68例患者分为三组，分别归类为轻度、中度或重度。在第一组中，即使在初次心导管检查时被诊断为轻度狭窄的患者，病变严重程度增加的情况也更为常见。在第二组中这种情况并不明显。与第二组相比，第一组卵圆孔未闭的发生率更高。与第二组相比，第一组中更多患者在重复心导管检查后需要手术。我们的数据表明，第一组中的轻度肺动脉狭窄病例在后期可能会变得严重，而在第二组中这种可能性较小。两组中中度和重度狭窄患者随着年龄增长病情可能保持不变或加重。
