Vogel M, Eger R, Klinner W, Bühlmeyer K
Department of Pediatrics, German Heart Center, Munich.
Pediatr Cardiol. 1990 Oct;11(4):191-4. doi: 10.1007/BF02238365.
As no long-term results of a blind opening up of the pulmonary valve either by balloon valvoplasty or closed Brock valvotomy have been published, we examined the outcome of 12 patients with valvar pulmonary stenosis 17 +/- 5 (11-22) years after surgery. The Brock valvotomy had been carried out at a mean age of 3 +/- 2.8 (0.2-8.5) years. The mean pressure gradient across the right ventricular outflow tract had been 116 +/- 45 (75-97) mmHg at the catheter study or 106 +/- 43 (40-160) mmHg as measured intraoperatively. The right ventricular pressure after the Brock procedure was measured in the operating room in five patients as 46 +/- 15 (30-60) mmHg. Seven patients had been recatheterized at a mean age of 9.5 +/- 2 (7-12.7) years; at that time the gradient across the pulmonary valve had been 20 +/- 14 (10-37) mmHg. At a mean age of 21.7 +/- 3 (15-26) years these and five further patients were reexamined by echo Doppler. This time the pressure gradient across the pulmonary valve was 13 +/- 6 (7-20) mmHg. Moderate pulmonary incompetence was present in four and mild incompetence in eight patients; two had mild tricuspid insufficiency. All except one patient, who had suffered a cerebrovascular accident before surgery, were in NYHA functional class 1 and pursuing a profession. From these data we conclude that the blind opening-up of the pulmonary valve achieves excellent long-term palliation.
由于尚未发表关于通过球囊瓣膜成形术或闭式布罗克瓣膜切开术盲目打开肺动脉瓣的长期结果,我们检查了12例患有瓣膜性肺动脉狭窄的患者在手术后17±5(11 - 22)年的结局。布罗克瓣膜切开术的平均实施年龄为3±2.8(0.2 - 8.5)岁。在导管检查时,右心室流出道的平均压力阶差为116±45(75 - 97)mmHg,术中测量为106±43(40 - 160)mmHg。在手术室中,对5例患者测量了布罗克手术后的右心室压力,为46±15(30 - 60)mmHg。7例患者在平均年龄9.5±2(7 - 12.7)岁时再次进行了导管检查;当时肺动脉瓣的压力阶差为20±14(10 - 37)mmHg。在平均年龄21.7±3(15 - 26)岁时,对这些患者以及另外5例患者进行了超声多普勒复查。此时,肺动脉瓣的压力阶差为13±6(7 - 20)mmHg。4例患者存在中度肺动脉瓣关闭不全,8例患者存在轻度关闭不全;2例患者存在轻度三尖瓣关闭不全。除1例在手术前发生过脑血管意外的患者外,所有患者均处于纽约心脏协会(NYHA)心功能1级并从事某种职业。根据这些数据我们得出结论,盲目打开肺动脉瓣可实现良好的长期姑息治疗效果。