Wennevold A, Jacobsen J R
Eur J Cardiol. 1978 Oct;8(3):371-8.
18 patients with mild and moderate valvular pulmonary stenosis diagnosed by heart catheterization before the age of 2 yr (mean 11.6 mth) were followed for 5 to 21 yr without operation. 15 cases had a repeat catheterization study after a mean interval of 10.7 yr. Of 7 cases with an initial right ventricular peak systolic pressure (RVSP) of 50 mm Hg or below, 6 had a decrease and 1 a moderate increase in RVSP. Of 8 cases with an initial RVSP of greater than 50 mm Hg 2 had a decrease, 2 had no change and 4 had a significant increase in RVSP; the latter subsequently underwent operation. Electrocardiography yielded some information, but neither roentgenography nor history was of any help in evaluating the severity of the stenosis at follow-up. As mild and moderate valvular pulmonary stenosis in infants and children below the age of 2 may progress and require operation a repeat heart catheterization is usually to be recommended later in childhood.
18例在2岁前（平均11.6个月）经心导管检查诊断为轻、中度瓣膜型肺动脉狭窄的患者，未经手术随访了5至21年。15例在平均10.7年的间隔后进行了重复心导管检查。初始右心室收缩压峰值（RVSP）为50 mmHg或更低的7例患者中，6例RVSP下降，1例中度升高。初始RVSP大于50 mmHg的8例患者中，2例下降，2例无变化，4例RVSP显著升高；后者随后接受了手术。心电图提供了一些信息，但在随访评估狭窄严重程度时，X线检查和病史均无帮助。由于2岁以下婴幼儿的轻、中度瓣膜型肺动脉狭窄可能进展并需要手术，通常建议在儿童期后期重复进行心导管检查。
