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[夏科。日期。传说与现实]

[Charcot. Dates. Legend and reality].

作者信息

Bonduelle M

出版信息

Hist Sci Med. 1994;28(4):289-95.

Abstract

This introductiion to the session devoted to Charcot reviews the important steps in his career: 1848, the internship, followed by the "chef de clinique" state (1852-53); the central hospital office in 1856; the agregation in 1860; the chair of pathological anatomy in 1872; the clinical chair in diseases of the nervous system in 1882. We review as well the milestones in his scientific work. His arrival in 1862 at the Salpêtrière which he would never leave; there in 1866, he started a "free" course which became the point of departure for his reputation. Taking advantage of histology together with a mastery of the anatomical-clinical method permitted him to achieve considerable progress with a few years (associating locomotor ataxia with lesions of the posterior roots and columns; acute and chronic progressive muscular atrophy with those of the anterior horn: separating multiple sclerosis from Parkinson's disease) which culminated in the masterful description of amyotrophic lateral sclerosis (1874), the pathological anatomy and physiology of the spinal cord (1873) and cerebral localisations of motor areas (1875). Beginning in 1878, he applied the nosological method to the study of hysteria, relying on the notion of "analogous anatomy" in seeking a correspondence between organic lesions and "dynamic lesions". In 1883 and 1884, his approach to aphasia led him to introduce beyond the anatomical-clinical fact a new speculative dimension, that of psycho-physiology. This he applied to interpret hysterical ailments and "psychic paralyses". The personality of Charcot is briefly sketched. In the arts as in politics, he was more of a conservative than an opportunist; authoritarian, shy, and brusque, gloomy and taciturn, he nontheless had a remarkable power to attract.

摘要

本次关于夏尔科的会议引言回顾了他职业生涯中的重要阶段

1848年的实习,随后是“临床主任”职位(1852 - 1853年);1856年进入中央医院办公室;1860年通过教师资格考试;1872年担任病理解剖学教授;1882年担任神经系统疾病临床教授。我们还回顾了他科学工作中的里程碑。1862年他来到萨尔佩特里埃医院并从未离开;1866年,他在那里开设了一门“免费”课程,这成为他声誉的起点。借助组织学并精通解剖 - 临床方法,他在几年内取得了显著进展(将运动性共济失调与后根和后索病变联系起来;将急性和慢性进行性肌肉萎缩与前角病变联系起来;将多发性硬化与帕金森病区分开来),最终出色地描述了肌萎缩侧索硬化症(1874年)、脊髓的病理解剖学和生理学(1873年)以及运动区的大脑定位(1875年)。从1878年开始,他将疾病分类学方法应用于癔症研究,依靠“类似解剖学”的概念来寻找器质性病变与“动态病变”之间的对应关系。1883年和1884年,他对失语症的研究方法使他在解剖 - 临床事实之外引入了一个新的思辨维度,即心理生理学维度。他将此应用于解释癔症性疾病和“精神性麻痹”。文中简要勾勒了夏尔科的性格特点。在艺术和政治方面,他与其说是机会主义者,不如说是保守派;他专制、害羞、唐突,忧郁且沉默寡言,但却有着非凡的吸引力。

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