Jarzabek Z, Sadowski W, Kańtoch M, Magrath D, Krawczyński K
Acta Virol. 1976 Oct;20(5):373-9.
The markers d, IST, EA1(OH)3 and rct at sub- and supraoptimal temperatures as well as neurovirulence (PMic) for monkeys was determined for strains isolated from children vaccinated with Leon 12a1b vaccine, their contacts and from paralytic cases. The strains were isolated at early and late phases of excretion. The changes concerned mainly rct determined at supraoptimal temperatures, d and PMic markers, especially in strains isolated at the late phase of excretion. The passage through the human alimentary tract did not change such markers as IST and EA1(OH)3. Some degree of correlation was observed between the rct 40.3, d and PMic markers.
测定了从接种莱昂12a1b疫苗的儿童、其接触者以及麻痹病例中分离出的毒株在亚最佳和超最佳温度下的标志物d、IST、EA1(OH)3和rct以及对猴子的神经毒力(PMic)。这些毒株是在排泄的早期和晚期分离出来的。变化主要涉及在超最佳温度下测定的rct、d和PMic标志物，尤其是在排泄后期分离出的毒株中。通过人体消化道并没有改变IST和EA1(OH)3等标志物。在rct 40.3、d和PMic标志物之间观察到一定程度的相关性。
