Moore P L, Goede A, Phillips D E, Carr R
Department of Otolaryngology/Head and Neck Surgery, Warwick Hospital, Warwick, UK.
J Laryngol Otol. 2001 Oct;115(10):859-61. doi: 10.1258/0022215011909198.
We report an atypical lipoma arising in the tongue of a 43-year-old man who presented with an indolent dorsal lingual swelling. Atypical lipomas contain multivacoulated lipoblasts, which distinguishes them from benign lipomas. The superficial location in this case distinguishes this tumour from well-differentiated liposarcoma, which is biologically similar in lacking the propensity for metastasis. The superficial location of atypical lipoma allows a complete resection, which is often not possible for the deep-seated counterpart. Atypical lipoma and well-differentiated liposarcoma, if left in situ, may undergo transition to de-differentiated liposarcoma. Atypical lipoma should be completely excised with a cuff of normal tissue in order to prevent repeated local recurrence and the possibility of de-differentiation.
我们报告了一例发生于一名43岁男性舌部的非典型脂肪瘤，该患者表现为舌背无痛性肿胀。非典型脂肪瘤含有多泡性脂肪母细胞，这使其有别于良性脂肪瘤。该病例中肿瘤位于浅表，这使其与高分化脂肪肉瘤相鉴别，高分化脂肪肉瘤在生物学行为上同样缺乏转移倾向。非典型脂肪瘤的浅表位置使其能够完整切除，而对于深部的同类肿瘤而言，完整切除往往是不可能的。非典型脂肪瘤和高分化脂肪肉瘤若原位留存，可能会转变为去分化脂肪肉瘤。非典型脂肪瘤应连带一圈正常组织完整切除，以防止局部反复复发以及去分化的可能性。
