Szmuness W, Much I, Prince A M, Hoofnagle J H, Cherubin C E, Harley E J, Block G H
Ann Intern Med. 1975 Oct;83(4):489-95. doi: 10.7326/0003-4819-83-4-489.
There is a significant excess of serologic evidence of hepatitis type B infection in two high-promiscuity populations: patients with venereal diseases and their unrelated sexual contacts (15% to 18%) and male, but not female, homosexuals (37% to 51%). Spouses of asymptomatic chronic carriers of antigen had a higher prevalence (26% to 28%) than spouses of noncarriers (10% to 11%); however, the prevalence in the former is relatively low when compared with rates seen in other relatives of carriers. Persons who had a higher-than-average probability of exposure to potentially infective partners or whose patterns of sexual behavior made such exposure more likely (large numbers of sexual partners, long duration of homosexuality, involvement in predominantly anal intercourse) were found to have serologic evidence of hepatitis B more frequently than those with other patterns of sexual behavior. This study showed a strong association between serologic evidence of type B hepatitis and patterns of sexual behavior. However, whether or not transmission of hepatitis type B virus occurs through vaginal intercourse could not be ascertained.
在两类高滥交人群中，乙型肝炎感染的血清学证据显著过量：性病患者及其非亲属性接触者（15%至18%）以及男性同性恋者（而非女性同性恋者）（37%至51%）。无症状慢性抗原携带者的配偶患病率（26%至28%）高于非携带者的配偶（10%至11%）；然而，与携带者的其他亲属相比，前者的患病率相对较低。与具有其他性行为模式的人相比，那些接触潜在感染性伴侣的概率高于平均水平或其性行为模式使这种接触更有可能发生的人（大量性伴侣、长期同性恋、主要参与肛交），更频繁地出现乙型肝炎的血清学证据。这项研究表明，乙型肝炎的血清学证据与性行为模式之间存在密切关联。然而，无法确定乙型肝炎病毒是否通过阴道性交传播。
