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冠状动脉搭桥手术中通过 transit time flow measurement 和术中血管造影进行移植物控制

Graft control by transit time flow measurement and intraoperative angiography in coronary artery bypass surgery.

作者信息

Hol P K, Fosse E, Mork B E, Lundblad R, Rein K A, Lingaas P S, Geiran O, Svennevig J L, Tonnessen T I, Nitter-Hauge S, Due-Tonnessen P, Vatne K, Smith H J

机构信息

Interventional Centre, Rikshospitalet, University of Oslo, N-0027 Oslo, Norway.

出版信息

Heart Surg Forum. 2001;4(3):254-7; discussion 257-8.

Abstract

BACKGROUND

The aim of this study was to compare the relationship between intraoperative transit time flow measurements and angiographic findings with long-term graft patency in 72 patients who underwent coronary artery bypass surgery.

METHODS

Transit time flow measurements with recording of mean flow and pulsatility indexes were performed after completion of the anastomoses. Coronary angiography was performed on-table while the patients were still in general anesthesia, and then at follow-up three months and 12 months after surgery. Based on angiography, the grafts were graded as type A (fully patent), type B (having more than 50% diameter reduction), or type O (occluded).

RESULTS

Of the 67 left internal mammary artery (LIMA) grafts, 51 (76%) were type A on-table, 14 (21%) were type B, and two (3%) were type O. Of the 57 saphenous vein grafts, 49 (86%) were type A, 7 (12%) were type B, and one (2%) was type O. For both LIMA and vein grafts, there were no differences in flow (p = 0.69 and 0.47, respectively) or pulsatility index (p = 0.79 and 0.83) between type A and B. There were also no differences in flow (p = 0.37 and 0.7) or pulsatility index (p = 0.37 and 0.24) between type B on-table that either normalized or persisted occluded at the follow-up. Transit time flow measurement failed to detect an occluded LIMA graft as shown by intraoperative angiography.

CONCLUSIONS

Blood flow measurements performed intraoperatively could not identify significant lesions in arterial or vein grafts, and could not predict graft patency. We have become cautious in interpreting flow measurements alone and combine blood flow recordings with intraoperative angiography in the assessment of graft quality.

摘要

背景

本研究旨在比较72例行冠状动脉搭桥手术患者术中通过时间血流测量与血管造影结果之间的关系,以及与长期移植物通畅情况的关系。

方法

吻合完成后进行通过时间血流测量,并记录平均血流和搏动指数。患者仍处于全身麻醉状态时在手术台上进行冠状动脉造影,然后在术后3个月和12个月进行随访造影。根据血管造影结果,移植物分为A 型(完全通畅)、B型(直径减少超过50%)或O型(闭塞)。

结果

67支左乳内动脉(LIMA)移植物中,51支(76%)在手术台上为A型,14支(21%)为B型,2支(3%)为O型。57支大隐静脉移植物中,49支(86%)为A型,7支(12%)为B型,1支(2%)为O型。对于LIMA和静脉移植物,A型和B型之间在血流(分别为p = 0.69和0.47)或搏动指数(p = 0.79和0.83)方面均无差异。在手术台上为B型且在随访时恢复正常或持续闭塞的移植物之间,血流(p = 0.37和0.7)或搏动指数(p = 0.37和0.24)也无差异。术中通过时间血流测量未能检测出术中血管造影所示的闭塞LIMA移植物。

结论

术中进行的血流测量无法识别动脉或静脉移植物中的显著病变,也无法预测移植物的通畅情况。我们在单独解释血流测量结果时变得谨慎,并在评估移植物质量时将血流记录与术中血管造影相结合。

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