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术中通过时间血流测量对冠状动脉手术中移植物短期通畅性的预测价值。

Predictive value of intraoperative transit-time flow measurement for short-term graft patency in coronary surgery.

作者信息

Di Giammarco Gabriele, Pano Marco, Cirmeni Sergio, Pelini Piero, Vitolla Giuseppe, Di Mauro Michele

机构信息

Division of Cardiac Surgery, University of Chieti-Pescara, Chieti, Italy.

出版信息

J Thorac Cardiovasc Surg. 2006 Sep;132(3):468-74. doi: 10.1016/j.jtcvs.2006.02.014.

Abstract

OBJECTIVE

The aim of this retrospective study was to evaluate the possibility to predict postoperative graft patency in coronary surgery by means of intraoperative transit-time flow measurement.

METHODS

Of 3567 patients submitted to isolated myocardial revascularization from June 1997 through June 2003, 157 (4.4%) underwent both intraoperative transit-time flow measurement and angiography at follow-up. Thirty-six have been revascularized on a beating heart. Three hundred four grafts, 227 arterial conduits, and 77 saphenous vein grafts were checked.

RESULTS

No patients died, and none of them had an acute myocardial infarction within 12 months after the operation. After a mean of 6.7 +/- 4.8 months from the operation, 266 grafts (group A) were completely functioning, whereas 38 grafts (group B) had failed. The transit-time flow parameters recorded in the latter group had significantly lower mean flow and higher pulsatility index and percentage of backward flow values at both univariate and multivariate analysis. Moreover, mean flow values of 15 mL/min or less, pulsatility index values of 3.0 or greater, and percentage of backward flow values of 3.0% or greater were found to be independent variables for higher incidence of graft failure.

CONCLUSIONS

Transit-time flow measurement represents a quick, easy, and reproducible method for intraoperative evaluation of graft function. The combination of the 3 major parameters (mean flow, pulsatility index, and percentage of backward flow) results in the chance to predict a graft failure (either anatomic or functional) within the first postoperative year.

摘要

目的

本回顾性研究的目的是评估通过术中渡越时间血流测量预测冠状动脉手术术后移植血管通畅性的可能性。

方法

在1997年6月至2003年6月接受单纯心肌血运重建的3567例患者中,157例(4.4%)在随访时同时进行了术中渡越时间血流测量和血管造影。36例在心脏跳动下进行了血运重建。检查了304条移植血管,其中227条动脉移植物和77条大隐静脉移植物。

结果

无患者死亡,且术后12个月内均无急性心肌梗死发生。术后平均6.7±4.8个月时,266条移植血管(A组)功能完全正常,而38条移植血管(B组)功能失败。在单因素和多因素分析中,后一组记录的渡越时间血流参数的平均流量显著降低,搏动指数和反向血流值百分比更高。此外,发现平均流量值≤15 mL/min、搏动指数值≥3.0以及反向血流值百分比≥3.0%是移植血管失败发生率较高的独立变量。

结论

渡越时间血流测量是一种快速、简便且可重复的术中评估移植血管功能的方法。3个主要参数(平均流量、搏动指数和反向血流百分比)的组合能够预测术后第一年移植血管失败(解剖或功能方面)的可能性。

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