Coleman A L, Brigatti L
Jules Stein Eye Institute, University of California, Los Angeles, California, USA.
Minerva Med. 2001 Oct;92(5):365-79.
Glaucoma is the leading cause of irreversible blindness worldwide. The World Health Organization reported in 1995 that 5.1 million persons were bilaterally blind from glaucoma. Its morbidity and prevalence make it a significant public health problem. Because it is a treatable condition, it is important that medical professionals be familiar with this disease, which in most cases is not associated with signs and symptoms that may alert the patient or the physician of its presence. Glaucoma is a progressive optic neuropathy that leads to blindness if left untreated. Risk factors include elevated intraocular pressure, advanced age, African ancestry and positive family history. Several types of glaucomas have been described: acute and chronic, secondary and primary. Primary (Chronic) Open Angle Glaucoma is the most common, with a prevalence in the USA of 1.55%. Blacks are 4 to 5 times more affected than whites. Treatment of glaucoma consists of topical or systemic intraocular pressure lowering agents, laser treatment or surgery. Primary Open Angle Glaucoma is an often-unrecognized disease due to its slow course and lack of symptoms. Because the decline in vision may be slowed but not restored by treatment, it is important that this condition be diagnosed early in its course.
青光眼是全球不可逆性失明的主要原因。世界卫生组织在1995年报告称,有510万人因青光眼而双目失明。其发病率和患病率使其成为一个重大的公共卫生问题。由于它是一种可治疗的疾病,医学专业人员熟悉这种疾病很重要,因为在大多数情况下,它不会出现可能提醒患者或医生其存在的体征和症状。青光眼是一种进行性视神经病变,如果不治疗会导致失明。风险因素包括眼压升高、高龄、非洲裔血统和家族病史阳性。已描述了几种类型的青光眼:急性和慢性、继发性和原发性。原发性(慢性)开角型青光眼最为常见,在美国的患病率为1.55%。黑人受影响的几率是白人的4至5倍。青光眼的治疗包括局部或全身使用降低眼压的药物、激光治疗或手术。原发性开角型青光眼由于病程缓慢且无症状,常常未被识别。由于治疗可减缓但无法恢复视力下降,因此在病程早期诊断这种疾病很重要。