Merrifield R, Keegan J, Firmin D, Yang G Z
Royal Society/Wolfson Foundation MIC Laboratory, Imperial College of Science, Technology and Medicine, London, UK.
Magn Reson Med. 2001 Nov;46(5):939-45. doi: 10.1002/mrm.1280.
Based on varying tissue contrasts at different RF flip angles, a new TrueFISP imaging strategy for cardiac function measurement is presented. A single breath-hold dual RF flip angle cine multi-slice TrueFISP imaging sequence was implemented which provides a significant increase in signal contrast between blood and myocardium. The increase in image contrast combined with different characteristics in RF response facilitates the delineation of cardiovascular borders. Based on this imaging strategy it is demonstrated how a simple 2D histogram clustering algorithm can be used for the fully automatic segmentation of the left ventricular (LV) blood pool. The method is validated with data acquired from 10 asymptomatic subjects, and the results are shown to be comparable to that of manual delineation by experienced observers.
基于不同射频翻转角下的组织对比度差异，提出了一种用于心脏功能测量的新型稳态自由感应衰减（TrueFISP）成像策略。实施了单次屏气双射频翻转角电影多层TrueFISP成像序列，该序列显著提高了血液与心肌之间的信号对比度。图像对比度的增加以及射频响应的不同特性有助于勾勒心血管边界。基于这种成像策略，展示了如何使用简单的二维直方图聚类算法对左心室血池进行全自动分割。该方法通过从10名无症状受试者获取的数据进行了验证，结果表明与经验丰富的观察者手动勾勒的结果相当。
