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纯单克隆IgG κ型冷球蛋白血症中的肾脏指纹沉积。

Finger print deposits of the kidney in pure monoclonal IgG kappa cryoglobulinemia.

作者信息

Ogihara T, Saruta T, Saito I, Abe S, Ozawa Y, Kato E, Sakaguchi H

出版信息

Clin Nephrol. 1979 Oct;12(4):186-90.

PMID:116789
Abstract

In a male patient with pure monoclonal IgG kappa cryoglobulin associated with the nephrotic syndrome, finger print deposits were observed in the subendothelial space and mesangial matrix of the kidney by electron microscopy. The structure was similar to a unique tubular crystal structure of IgGl kappa cryoglobulin which was reported by Bogaars et al. [1973] in the serum of a patient with multiple myeloma. It was therefore supposed that the finger print deposits in the kidney of this patient were the precipitation of the monoclonal IgG kappa cryoglobulin in serum.

摘要

在一名患有与肾病综合征相关的纯单克隆IgG κ型冷球蛋白血症的男性患者中,通过电子显微镜观察到在肾脏的内皮下间隙和系膜基质中有指纹状沉积物。该结构类似于Bogaars等人[1973年]在一名多发性骨髓瘤患者血清中报道的IgG1 κ型冷球蛋白独特的管状晶体结构。因此推测该患者肾脏中的指纹状沉积物是血清中单克隆IgG κ型冷球蛋白的沉淀。

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