Bodner M, Muftuler L T, Nalcioglu O, Shaw G L
Department of Physics, University of California, Irvine, 92697, USA.
Neurol Res. 2001 Oct;23(7):683-90. doi: 10.1179/016164101101199108.
Behavioral studies, motivated by columnar cortical model predictions, have given evidence for music causally enhancing spatial-temporal reasoning. A wide range of behavioral experiments showed that listening to a Mozart Sonata (K.448) gave subsequent enhancements. An EEG coherence study gave evidence for a carryover from that Mozart Sonata listening condition to the subsequent spatial-temporal task in specific cortical regions. Here we present fMRI studies comparing cortical blood flow activation by the Mozart Sonata vs. other music. In addition to expected temporal cortex activation, we report dramatic statistically significant differences in activation by the Mozart Sonata (in comparison to Beethoven's Fur Elise and 1930s piano music) in dorsolateral pre-frontal cortex, occipital cortex and cerebellum, all expected to be important for spatial-temporal reasoning. It would be of great interest to explicitly test this expectation. We propose an fMRI study comparing (subject by subject) brain areas activated in music listening conditions and in spatial-temporal tasks.
受柱状皮层模型预测启发的行为学研究，已为音乐能因果性地增强时空推理提供了证据。一系列行为实验表明，聆听莫扎特奏鸣曲（K.448）能带来后续能力提升。一项脑电图相干性研究为从该莫扎特奏鸣曲聆听状态到后续特定皮层区域时空任务的延续效应提供了证据。在此，我们展示功能磁共振成像（fMRI）研究，比较莫扎特奏鸣曲与其他音乐引起的皮层血流激活情况。除了预期的颞叶皮层激活外，我们报告称，与贝多芬的《致爱丽丝》和20世纪30年代的钢琴音乐相比，莫扎特奏鸣曲在背外侧前额叶皮层、枕叶皮层和小脑中的激活存在显著的统计学差异，而这些区域都被认为对时空推理很重要。明确验证这一预期将非常有趣。我们提议开展一项功能磁共振成像研究，逐个受试者地比较在音乐聆听状态和时空任务中激活的脑区。
