Popescu Mihai, Otsuka Asuka, Ioannides Andreas A
Laboratory for Human Brain Dynamics, Brain Science Institute, RIKEN, Wako, Saitama 351-0198, Japan.
Neuroimage. 2004 Apr;21(4):1622-38. doi: 10.1016/j.neuroimage.2003.11.002.
There are formidable problems in studying how 'real' music engages the brain over wide ranges of temporal scales extending from milliseconds to a lifetime. In this work, we recorded the magnetoencephalographic signal while subjects listened to music as it unfolded over long periods of time (seconds), and we developed and applied methods to correlate the time course of the regional brain activations with the dynamic aspects of the musical sound. We showed that frontal areas generally respond with slow time constants to the music, reflecting their more integrative mode; motor-related areas showed transient-mode responses to fine temporal scale structures of the sound. The study combined novel analysis techniques designed to capture and quantify fine temporal sequencing from the authentic musical piece (characterized by a clearly defined rhythm and melodic structure) with the extraction of relevant features from the dynamics of the regional brain activations. The results demonstrated that activity in motor-related structures, specifically in lateral premotor areas, supplementary motor areas, and somatomotor areas, correlated with measures of rhythmicity derived from the music. These correlations showed distinct laterality depending on how the musical performance deviated from the strict tempo of the music score, that is, depending on the musical expression.
研究“真实”音乐如何在从毫秒到一生的广泛时间尺度上与大脑相互作用存在巨大问题。在这项研究中，我们记录了受试者长时间（数秒）聆听音乐时的脑磁图信号，并开发并应用了一些方法，将大脑区域激活的时间进程与音乐声音的动态方面进行关联。我们发现额叶区域通常以较慢的时间常数对音乐做出反应，这反映了它们更具整合性的模式；与运动相关的区域对声音的精细时间尺度结构表现出瞬态模式反应。该研究将旨在从真实音乐作品（具有明确界定的节奏和旋律结构）中捕捉和量化精细时间序列的新颖分析技术，与从大脑区域激活动态中提取相关特征相结合。结果表明，与运动相关结构中的活动，特别是外侧运动前区、辅助运动区和躯体运动区的活动，与从音乐中得出的节奏性测量值相关。这些相关性表现出明显的偏侧性，具体取决于音乐表演与乐谱严格节奏的偏离程度，即取决于音乐表现力。
