Hamada T, Kondo K, Saito S, Kitamura S
Department of Gastroenterology, Social Health Insurance Medical Center, Tokyo, Japan.
Nihon Geka Gakkai Zasshi. 2001 Oct;102(10):745-8.
Endoscopic mucosal resection (EMR) has made it possible to perform radical resection of early gastric cancers in resectable cases. To extend the indications for EMR, we discuss the following. 1) Three hundred fifty-seven patients with 389 lesions of early gastric cancer who were treated either with whole-block resection or partial resection were analyzed to evaluate the recurrence rate by the method. The recurrence rate was 15.1% of 139 lesions treated with whole-block resection and 8.0% of 250 lesions treated with both methods. It is considered that partial resection with the marking procedure is very important to remove the cancer completely. 2) The management of recurrent cancer recognized at follow-up examination after EMR is very important for patients because these are operable cases. Of recurrent cancers, 80.5% were diagnosed within one year after EMR, and therefore during this period careful follow-up examinations should be done. The therapy used to treat these recurrent cancers was re-EMR in 26 cases and surgical operation in 15 cases. 3) Problems still remain concerning how to manage cancer invading the submucosa diagnosed after EMR.
内镜黏膜切除术(EMR)使可切除的早期胃癌根治性切除成为可能。为扩大EMR的适应证,我们讨论以下内容。1)对357例患有389处早期胃癌病变且接受整块切除或部分切除治疗的患者进行分析,以评估该方法的复发率。整块切除治疗的139处病变复发率为15.1%,两种方法治疗的250处病变复发率为8.0%。认为采用标记程序的部分切除对于完全切除癌症非常重要。2)对于患者而言,EMR后随访检查中发现的复发性癌症的处理非常重要,因为这些是可手术的病例。在复发性癌症中,80.5%在EMR后一年内被诊断出来,因此在此期间应进行仔细的随访检查。用于治疗这些复发性癌症的治疗方法是再次EMR 26例,手术治疗15例。3)关于如何处理EMR后诊断出的侵犯黏膜下层的癌症,问题仍然存在。