Dong Q, Shen X Y
Institute of Space Medico-Engineering, Beijing 100094, China.
Space Med Med Eng (Beijing). 2001 Aug;14(4):298-302.
The reduction of red blood cell mass is a main change of hematology under microgravity. It is considered that the decrease of erythroid cell production is the key cause. The studies on reticulocytes, Price-Jones curve, ferrum turn over, cytology of bone marrow and Erythropoietin (Epo) level suggested the suppression of erythropoiesis was due to microgravity. The mechanisms about it and the aspects of research in the future were discussed briefly.
红细胞数量减少是微重力环境下血液学的主要变化。一般认为,红系细胞生成减少是关键原因。对网织红细胞、普赖斯 - 琼斯曲线、铁代谢、骨髓细胞学及促红细胞生成素(Epo)水平的研究表明,红细胞生成受抑制是由微重力所致。本文简要讨论了其机制及未来的研究方向。