Mustafa D, Lucas V S, Junod P, Evans R, Mason C, Roberts G J
Department of Paediatric Dentistry, Eastman Dental Institute for Oral Health Care Sciences, University College London, 256 Gray's Inn Road, London WC1X 8LD, England.
Cleft Palate Craniofac J. 2001 Nov;38(6):629-35. doi: 10.1597/1545-1569_2001_038_0629_tdhacr_2.0.co_2.
To compare levels of dental caries, bacterial dental plaque, gingivitis, enamel defects, and caries-related microflora in children with and without craniosynostosis.
Fifty-seven children with craniosynostosis and their matched controls.
The decayed, missing, and filled teeth and surfaces in both the deciduous (dmfs and dmft) and the permanent dentition (DMFS and DMFT). The plaque and gingivitis scores and developmental enamel defects were also recorded. The caries-related microflora was sampled using an alginate swab and the prevalence of Streptococcus mutans and Lactobacillus and Candida species were recorded.
The dmfs (p <.02) and dmft (p <.01) were significantly greater in the control children. The plaque score for the deciduous dentition only (p <.02) and also the gingivitis score for the permanent teeth only (p <.008) in the craniosynostosis group were significantly greater. The total aerobic bacterial count (p <.004), anaerobic count (p <.002), and Candida count (p <.05) were significantly greater in the control group. The proportion of S. mutans both as a percentage of the total anaerobic count (p <.04) and the total streptococcal count (p <.05) was significantly greater in the control group.
比较患有和未患有颅缝早闭症儿童的龋齿、牙菌斑、牙龈炎、牙釉质缺陷以及与龋齿相关的微生物群落水平。
57名患有颅缝早闭症的儿童及其匹配的对照组。
乳牙列（dmfs和dmft）和恒牙列（DMFS和DMFT）中的龋失补牙数及补牙面数。还记录了菌斑和牙龈炎评分以及牙釉质发育缺陷情况。使用藻酸盐拭子采集与龋齿相关的微生物样本，并记录变形链球菌、乳酸杆菌和念珠菌属的患病率。
对照组儿童的dmfs（p <.02）和dmft（p <.01）显著更高。颅缝早闭症组仅乳牙列的菌斑评分（p <.02）以及仅恒牙的牙龈炎评分（p <.008）显著更高。对照组的需氧菌总数（p <.004）、厌氧菌总数（p <.002）和念珠菌数（p <.05）显著更高。对照组中变形链球菌占总厌氧菌数的百分比（p <.04）和占总链球菌数的百分比（p <.05）显著更高。
