Lucas V S, Contreras A, Loukissa M, Roberts G J
Department of Oral Medicine, Eastman Dental Institute for Oral Health Care Sciences, University of London, 256 Gray's Inn Road, London WC1X 8LD.
ASDC J Dent Child. 2001 Jul-Aug;68(4):263-7, 229.
The purpose of this study was to investigate the dental caries, plaque and gingivitis indices and caries related oral flora in children with classic phenylketonuria. Forty-one children at The Great Ormond Street Hospital for Children and controls were included in the study. The main findings were: No significant difference in the decayed, missing and filled surfaces of the primary and permanent teeth between the phenylketonuria children and the controls. A significantly greater mean plaque score for the control children compared with the phenylketonuria children (p < 0.01) for the permanent teeth only. A significantly greater number of white opacities in the permanent teeth of the phenylketonuria group compared with the control group (p < 0.02). No significant differences in the caries related microflora.
本研究的目的是调查经典型苯丙酮尿症患儿的龋齿、菌斑和牙龈炎指数以及与龋齿相关的口腔菌群。大奥蒙德街儿童医院的41名患儿及对照组纳入了本研究。主要研究结果如下：苯丙酮尿症患儿与对照组在乳牙和恒牙的龋失补牙面方面无显著差异。仅在恒牙方面，对照组患儿的平均菌斑评分显著高于苯丙酮尿症患儿（p < 0.01）。与对照组相比，苯丙酮尿症组恒牙中白色浑浊的数量显著更多（p < 0.02）。在与龋齿相关的微生物群方面无显著差异。
