Arndt S S, Surjo D
University of Cologne, Anatomy II, Cognitive Neurobiology, Joseph-Stelzmann-Str. 9, 50931 Cologne, Germany.
Behav Brain Res. 2001 Nov 1;125(1-2):39-42. doi: 10.1016/s0166-4328(01)00285-6.
The number of genetically engineered mice is constantly increasing. These animals play an important role in the development of useful models for human diseases. The Mutant Mice Behaviour-network, "MMB", was founded as a non-profit, international forum for presenting and discussing the behavioural phenotyping of these mice. The internet-based network will provide a standardised database that includes detailed descriptions of all parameters that might affect the behaviour of genetically engineered mice. This will lead to comprehensible and reproducible tests and, in the future, might lead to an interdisciplinary consensus on methods for mouse behavioural phenotyping.
基因工程小鼠的数量在不断增加。这些动物在人类疾病有用模型的开发中发挥着重要作用。突变小鼠行为网络(“MMB”)作为一个非营利性的国际论坛而成立,用于展示和讨论这些小鼠的行为表型分析。这个基于互联网的网络将提供一个标准化数据库,其中包括可能影响基因工程小鼠行为的所有参数的详细描述。这将带来可理解且可重复的测试,并且在未来,可能会就小鼠行为表型分析方法达成跨学科的共识。