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黑腹果蝇中的遗传不稳定性:串联重复作为链内交换的监测指标。

Genetic instability in Drosophila melanogaster: tandem duplications as monitors of intrastrand exchange.

作者信息

Green M M, Lefevre G

出版信息

Chromosoma. 1979 Oct 1;74(3):329-35. doi: 10.1007/BF01190747.

DOI:10.1007/BF01190747
PMID:116829
Abstract

Two tandem duplications of the X chromosome associated with the white eye color locus are described. In heterozygous females both revert to a nonduplicated chromosome without detectable meiotic recombination. Clustering of revertants suggests the reversion event occurs in the germ line prior to meiosis. Similarly in males one duplication also reverts with clustering implying a premeiotic event. Revertant X chromosomes derived from males are either nonduplicated or deleted. Intrastrand exchange can account for some but not all revertants recovered.

摘要

描述了与白眼颜色位点相关的X染色体的两个串联重复。在杂合雌性中,两者都恢复为非重复染色体,且未检测到减数分裂重组。回复体的聚集表明回复事件发生在减数分裂之前的生殖系中。同样,在雄性中,一个重复也会随着聚集而回复,这意味着是减数分裂前的事件。来自雄性的回复X染色体要么是非重复的,要么是缺失的。链内交换可以解释部分但不是所有回收的回复体。

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本文引用的文献

1
Tandem duplications in Drosophila melanogaster II. Meiotic pairing and exchange in heterozygous tandem duplications.果蝇中的串联重复 II. 杂合串联重复的减数分裂配对和交换。
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INTRACHROMOSOMAL EXCHANGE AT THE BAR LOCUS IN DROSOPHILA.果蝇中棒眼基因座处的染色体内交换
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Putative non-reciprocal crossing over in Drosophila melanogaster.黑腹果蝇中假定的非相互交换
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Some genetic properties of intrachromosomal recombination.染色体内重组的一些遗传特性。
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Genetic analysis of the aberrant behavior of an X-chromosome duplication in the germ line of Drosophila melanogaster males.黑腹果蝇雄性生殖系中X染色体重复异常行为的遗传分析。
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