Tao Y, Hartl D L, Laurie C C
Department of Developmental, Cell, and Molecular Biology, Duke University, Durham, NC 27708, USA.
Proc Natl Acad Sci U S A. 2001 Nov 6;98(23):13183-8. doi: 10.1073/pnas.231478798. Epub 2001 Oct 30.
Sex-ratio distortion is the most common form of non-Mendelian segregation observed in natural populations. It may occur even more frequently than direct observations suggest, because the dysgenic population consequences of a biased sex ratio are expected to result in the rapid evolution of suppressors, resulting in suppressed or "cryptic" segregation distortion. Here we report evidence for cryptic sex-ratio distortion that was discovered by introgressing segments of the genome of Drosophila mauritiana into the genome of Drosophila simulans. The autosomal suppressor of sex-ratio distortion, which is also associated with a reduction in hybrid male fertility, has been genetically localized to a region smaller than 80-kb pairs in chromosome 3.
性别比例畸变是自然种群中观察到的最常见的非孟德尔分离形式。它的发生频率可能比直接观察到的还要高,因为性别比例偏差的不良种群后果预计会导致抑制因子的快速进化,从而导致抑制或“隐性”的分离畸变。在这里,我们报告了隐性性别比例畸变的证据,这是通过将毛里求斯果蝇的基因组片段渗入拟果蝇的基因组中发现的。性别比例畸变的常染色体抑制因子,也与杂种雄性育性降低有关,已在遗传上定位到3号染色体上小于80千碱基对的区域。