Hari C K, Hanif J, Frosh A
Department of Otolaryngology, Southmead Hospital, Bristol.
Int J Clin Pract. 2001 Oct;55(8):571-2.
A 23-year-old female with progressive sensorineural hearing loss developed widespread blistering eruptions while under evaluation for the hearing loss. The lesions showed findings characteristic of linear IgA disease (LAD) on histochemical studies. Linear IgA disease is a dapsone responsive autoimmune subepidermal blistering disease characterised by linear IgA deposits in the basement membrane zone. The complete spectrum of this systemic disease is still not clear and this is the first report of association between LAD and sensorineural deafness.
一名23岁进行性感音神经性听力损失的女性在接受听力损失评估时出现了广泛的水疱性皮疹。组织化学研究显示这些皮损具有线状IgA疾病（LAD）的特征性表现。线状IgA疾病是一种对氨苯砜有反应的自身免疫性表皮下大疱性疾病，其特征是在基底膜带出现线状IgA沉积。这种全身性疾病的全貌仍不清楚，这是关于LAD与感音神经性耳聋关联的首例报告。
