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[胃肠道类癌的药物治疗]

[Drug therapy of carcinoids of the gastrointestinal tract].

作者信息

Engelbach M, Heusel C P, Kriegsmann J, Both S, Walgenbach S

机构信息

Klinik und Poliklinik Innere Medizin, Schwerpunkt Endokrinologie und Stoffwechselerkrankungen, Johannes-Gutenberg-Universität, Mainz.

出版信息

Zentralbl Chir. 2001 Sep;126(9):682-5. doi: 10.1055/s-2001-18240.

Abstract

Carcinoid tumors are rare and slowly growing neuroendocrine tumors of the foregut, midgut and hindgut. Drug therapy is of special importance in patients with inoperable metastasising disease. This palliative therapy is aimed at reduction of the hormone-dependent symptoms and inhibition of tumor growth. Somatostatin analogues, alpha-interferon and various chemotherapeutic agents are used for this purpose. Drug therapy can be supplemented by surgical and radiological intervention through interdisciplinary cooperation of the surgeon, radiologist, endocrinologist and gastroenterologist.

摘要

类癌肿瘤是前肠、中肠和后肠罕见且生长缓慢的神经内分泌肿瘤。对于无法手术的转移性疾病患者,药物治疗尤为重要。这种姑息治疗旨在减轻激素依赖性症状并抑制肿瘤生长。为此使用生长抑素类似物、α干扰素和各种化疗药物。通过外科医生、放射科医生、内分泌科医生和胃肠病学家的跨学科合作,药物治疗可辅以手术和放射介入治疗。

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