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Novel metabolic products of cyclophosphamide in human urine.

作者信息

Cox P J, Levin L

出版信息

Biochem Pharmacol. 1975 Jun 15;24(11-12):1233-5. doi: 10.1016/0006-2952(75)90068-4.

DOI:10.1016/0006-2952(75)90068-4
PMID:1169947
Abstract
摘要

相似文献

1
Novel metabolic products of cyclophosphamide in human urine.
Biochem Pharmacol. 1975 Jun 15;24(11-12):1233-5. doi: 10.1016/0006-2952(75)90068-4.
2
Quantitation by gas chromatography-chemical ionization mass spectrometry of cyclophosphamide, phosphoramide mustard, and nornitrogen mustard in the plasma and urine of patients receiving cyclophosphamide therapy.采用气相色谱-化学电离质谱法对接受环磷酰胺治疗的患者血浆和尿液中环磷酰胺、磷酰胺氮芥和去甲氮芥进行定量分析。
Cancer Res. 1978 Feb;38(2):408-15.
3
Approaches to the pharmacokinetics of cyclophosphamide (NSC 26271): Quantitation of metabolites.
Cancer Treat Rep. 1976 Apr;60(4):403-8.
4
Identification and pharmacokinetics of cyclophosphamide (NSC-26271) metabolites in vivo.
Cancer Treat Rep. 1976 Apr;60(4):415-22.
5
Characterization of the major sheep urinary metabolites of cyclophosphamide, a defleecing chemical.一种脱毛化学品环磷酰胺的主要绵羊尿液代谢产物的表征
J Agric Food Chem. 1971 Jul-Aug;19(4):788-90. doi: 10.1021/jf60176a038.
6
Isolation and mass spectral identification of blood metabolites of cyclophosphamide: evidence for phosphoramide mustard as the biologically active metabolite.
Biomed Mass Spectrom. 1975 Feb;2(1):46-52. doi: 10.1002/bms.1200020109.
7
A simple, small scale cytotoxicity test, and its uses in drug metabolism studies.一种简单的小规模细胞毒性试验及其在药物代谢研究中的应用。
Biochem Pharmacol. 1974 Jan 1;23(1):131-8. doi: 10.1016/0006-2952(74)90319-0.
8
Identification of new metabolites of phosphoramide and nor-nitrogen mustards and cyclophosphamide in rat urine using ion cluster techniques.使用离子簇技术鉴定大鼠尿液中磷酰胺、去氮氮芥和环磷酰胺的新代谢物。
Biomed Environ Mass Spectrom. 1986 Mar;13(3):145-54. doi: 10.1002/bms.1200130310.
9
Some studies of the active intermediates formed in the microsomal metabolism of cyclophosphamide and isophosphamide.一些关于环磷酰胺和异环磷酰胺微粒体代谢过程中形成的活性中间体的研究。
Biochem Pharmacol. 1974 Jan 1;23(1):115-29. doi: 10.1016/0006-2952(74)90318-9.
10
Isolation and identification of a stabilized derivative of aldophosphamide, a major metabolite of cyclophosphamide.
Cancer Res. 1974 Nov;34(11):2933-5.

引用本文的文献

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Comparative metabolism of cyclophosphamide and ifosfamide in the mouse using UPLC-ESI-QTOFMS-based metabolomics.基于 UPLC-ESI-QTOFMS 的代谢组学研究在小鼠体内环磷酰胺和异环磷酰胺的比较代谢。
Biochem Pharmacol. 2010 Oct 1;80(7):1063-74. doi: 10.1016/j.bcp.2010.06.002. Epub 2010 Jun 10.
2
Ames' mutagenic activity in recycled water from an Israeli water reclamation project.艾姆斯试验在以色列水回收项目的再生水中的诱变活性。
Bull Environ Contam Toxicol. 1980 Jan;24(1):168-75. doi: 10.1007/BF01608093.
3
Comparison of XAD-2 column and blue cotton batch techniques for isolation of metabolites of 2-amino-3-methylimidazo[4,5-f]quinoline.
用于分离2-氨基-3-甲基咪唑[4,5-f]喹啉代谢物的XAD-2柱和蓝色棉批量技术的比较。
Jpn J Cancer Res. 1988 Jan;79(1):42-8. doi: 10.1111/j.1349-7006.1988.tb00009.x.
4
Pharmacokinetics of phenytoin and liver cytochrome P-450 levels in mice after single doses of Corynebacterium parvum [proceedings].单次注射短小棒状杆菌后小鼠体内苯妥英的药代动力学及肝细胞色素P-450水平[会议论文]
Br J Pharmacol. 1979 Nov;67(3):470P-472P.
5
Excretion patterns of alkylating metabolites in urine following cyclophosphamide treatment of tumor patients: influence of application route, dosage, liver and kidney function.
J Cancer Res Clin Oncol. 1979 Jul 27;94(3):277-86. doi: 10.1007/BF00419287.
6
Concentration of mutagens from urine by absorption with the nonpolar resin XAD-2: cigarette smokers have mutagenic urine.用非极性树脂XAD - 2吸收法浓缩尿液中的诱变剂：吸烟者的尿液具有致突变性。
Proc Natl Acad Sci U S A. 1977 Aug;74(8):3555-9. doi: 10.1073/pnas.74.8.3555.