Urík Milan, Bartoš Michal, Šikolová Soňa, Jančíková Jana, Perceová Klára, Jarkovský Jiří, Klabusayová Eva, Štourač Petr, Jabandžiev Petr
Department of Paediatric Otorhinolaryngology, University Hospital Brno and Faculty of Medicine, Masaryk University, 61300 Brno, Czech Republic.
Institute of Biostatistics and Analyses, Faculty of Medicine, Masaryk University, 61300 Brno, Czech Republic.
Children (Basel). 2021 Mar 21;8(3):242. doi: 10.3390/children8030242.
Postoperative bleeding is a common and potentially life-threatening complication. Precise identification of risk factors in addition to the basic ones, such as coagulation parameters, is certainly very desirable.
The aim of this study was to identify other possible risk factors for bleeding after adenoidectomy in children.
This observational prospective study enrolled children undergoing adenoidectomy from October 2019 to February 2020, then evaluated the influence of possible risk factors for bleeding.
Tertiary pediatric otorhinolaryngology center.
A total of 288 children aged 0-18 years undergoing adenoidectomy for recurrent upper respiratory tract infections, recurrent acute otitis media, secretory otitis media, and obstructive sleep apnea syndrome.
Increased blood pressure and time of surgery were identified as risk factors for bleeding after adenoidectomy.
Elevated systolic ( = 0.046), diastolic ( = 0.012), and mean arterial blood pressure ( = 0.007) (Mann-Whitney U test) as adjusted for age-specific distributions and with corrections for height and weight, as well as time length of surgery ( < 0.001) (Fisher's exact test) were revealed as statistically significant risk factors for postoperative bleeding. Atmospheric pressure, surgeon's level of experiences, chronic inflammatory content in adenoid vegetation (AV), size of AV, recidivism of AV, recurrent infections of the upper respiratory tract, type of anesthesia, long-term using of drugs, and positive coagulation questionnaire or pathology in standard coagulation tests were not found to be risk factors for bleeding after adenoidectomy.
In this prospective study within a well-defined population of children, we evaluated increased blood pressure and time of surgery as risk factors for bleeding after adenoidectomy. These data bring new information that complements current knowledge in this field.
术后出血是一种常见且可能危及生命的并发症。除了诸如凝血参数等基本因素外,精确识别风险因素无疑是非常必要的。
本研究旨在确定儿童腺样体切除术后出血的其他可能风险因素。
这项观察性前瞻性研究纳入了2019年10月至2020年2月期间接受腺样体切除术的儿童,然后评估了出血可能风险因素的影响。
三级儿科耳鼻喉科中心。
共有288名0至18岁的儿童因复发性上呼吸道感染、复发性急性中耳炎、分泌性中耳炎和阻塞性睡眠呼吸暂停综合征接受腺样体切除术。
血压升高和手术时间被确定为腺样体切除术后出血的风险因素。
经年龄特异性分布调整并校正身高和体重后,收缩压升高(P = 0.046)、舒张压升高(P = 0.012)和平均动脉血压升高(P = 0.007)(曼-惠特尼U检验),以及手术时长(P < 0.001)(费舍尔精确检验)被揭示为术后出血的统计学显著风险因素。未发现大气压、外科医生的经验水平、腺样体组织中的慢性炎症含量、腺样体组织大小、腺样体组织复发、上呼吸道反复感染、麻醉类型、长期用药以及标准凝血试验中的凝血问卷阳性或病理结果是腺样体切除术后出血的风险因素。
在这项针对明确界定的儿童群体的前瞻性研究中,我们评估了血压升高和手术时间作为腺样体切除术后出血的风险因素。这些数据带来了补充该领域现有知识的新信息。