Fraser I S, Warner P, Marantos P A
Sydney Centre for Reproductive Health Research, Family Planning NSW, Sydney, Australia.
Obstet Gynecol. 2001 Nov;98(5 Pt 1):806-14. doi: 10.1016/s0029-7844(01)01581-2.
To examine the relationship between total fluid volume at menstruation and the volume of blood loss, and to assess the feasibility of using total fluid volume to estimate menstrual blood loss.
Fifty-three women were studied over two menstrual periods each. Hemoglobin in menstrual pads and tampons was measured using the alkaline hematin technique; total menstrual fluid volume was simultaneously measured using a weighing technique and meticulous care to avoid evaporation.
Despite period-to-period change in measured total menstrual fluid and menstrual blood loss volumes, there was a significant correlation between total fluid volume and blood loss (r =.93, P <.001). Blood comprised 48% of total menstrual flow for women with moderately heavy blood loss (>60 mL) and 50% for women with excessive blood loss (>100 mL). Regression estimation of blood loss from total fluid volume was reasonably accurate. For clinical purposes, estimated blood volumes correctly classified 98% of periods in terms of actual blood loss as normal (<60 mL blood), moderately heavy (60-100 mL), or excessive (>100 mL).
If total fluid volume is measured carefully, the estimate of actual blood loss is sufficiently accurate for clinical purposes. This simple technique has considerable clinical potential, and inexpensive commercial packs for this purpose could easily be developed.
研究月经期总液体量与失血量之间的关系，并评估使用总液体量来估计月经量的可行性。
对53名女性进行了研究，每位女性观察两个月经周期。采用碱性高铁血红素技术测量月经垫和卫生棉条中的血红蛋白；同时使用称重技术并极其小心地避免蒸发来测量月经总液体量。
尽管测量的月经总液体量和月经量在不同周期有所变化，但总液体量与失血量之间存在显著相关性（r = 0.93，P < 0.001）。对于中度失血（>60 mL）的女性，血液占月经总流量的48%，对于大量失血（>100 mL）的女性，这一比例为50%。根据总液体量对失血量进行回归估计相当准确。出于临床目的，估计的血量能将98%的月经周期根据实际失血量正确分类为正常（<60 mL血）、中度失血（60 - 100 mL）或大量失血（>100 mL）。
如果仔细测量总液体量，对于临床目的而言，实际失血量的估计足够准确。这种简单技术具有相当大的临床潜力，并且为此目的开发廉价的商业包装很容易实现。
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