Siebert U, Rothenbacher D, Daniel U, Brenner H
Department of Epidemiology, University of Ulm, Ulm, Germany.
Occup Environ Med. 2001 Dec;58(12):774-9. doi: 10.1136/oem.58.12.774.
To assess the potential of a healthy worker survivor effect due to differential occupational mobility in a cohort of construction workers.
A cohort of 10 809 male employees in the German construction industry aged 15-64 years was followed up for occupational mobility, early retirement due to permanent disability, and total mortality from 1986 to 1994. Using the Cox's proportional hazards model of relative rates (RRs) with 95% confidence intervals (95% CIs) of occupational mobility, early retirement and total mortality were estimated according to medical diagnoses at baseline after adjustment for various covariates.
During follow up, 2472 subjects changed employment, 359 employees were granted a disability pension for health reasons and 188 subjects died. A wide range of chronic diseases was associated with increased rates of early retirement and total mortality but not occupational mobility. However, a healthy worker survivor effect was identified related to disorders of the back and spine (ninth revision of the international classification of diseases, ICD-9, code 720-4), a common predictor of both occupational mobility (RR 1.17, 95% CI 1.04 to 1.32) and early retirement (RR 1.50, 95% CI 1.20 to 1.88). In total, there were about as many events of occupational changes (n = 41) as events of early retirement due to permanent disability (n = 39) significantly attributable to disorders of the back and spine. Differential occupational mobility preceded differential early retirement due to permanent disability by more than one decade.
These findings show the need to consider a healthy worker survivor effect due to occupational mobility in occupational epidemiological research. Furthermore these results underline the necessity of further health promotion targeting work related conditions in the construction industry.
评估在一群建筑工人中,因职业流动性差异导致的健康工人幸存者效应的可能性。
对1986年至1994年间德国建筑业10809名年龄在15 - 64岁的男性雇员进行队列研究,跟踪其职业流动性、因永久性残疾提前退休情况以及全因死亡率。使用Cox比例风险模型的相对率(RRs)及95%置信区间(95% CIs),在对各种协变量进行调整后,根据基线时的医学诊断估计职业流动性、提前退休和全因死亡率。
随访期间,2472名受试者更换了工作,359名雇员因健康原因获得了残疾抚恤金,188名受试者死亡。多种慢性病与提前退休率和全因死亡率的增加相关,但与职业流动性无关。然而,发现了与背部和脊柱疾病(国际疾病分类第九版,ICD - 9,编码720 - 4)相关的健康工人幸存者效应,这是职业流动性(RR 1.17,95% CI 1.04至1.32)和提前退休(RR 1.50,95% CI 1.20至1.88)的常见预测因素。总的来说,因背部和脊柱疾病导致的职业变动事件(n = 41)与因永久性残疾提前退休事件(n = 39)数量大致相同。因永久性残疾导致的提前退休差异比职业变动差异晚十多年。
这些研究结果表明,在职业流行病学研究中有必要考虑因职业流动性导致的健康工人幸存者效应。此外,这些结果强调了针对建筑业与工作相关状况进一步开展健康促进的必要性。