Mota M M, Rodriguez A
Department of Pathology, New York University, 550 First Avenue, New York, NY 10016, USA.
Microbes Infect. 2001 Nov;3(13):1123-8. doi: 10.1016/s1286-4579(01)01473-3.
In what appears to be an essential prelude to establish a successful infection in the mammalian host, Plasmodium sporozoites move rapidly through several host cells breaching the cell plasma membranes in the process. This mode of invasion precedes the 'traditional' mode in which the sporozoite enters by invagination of the host cell membrane and develops within a parasitophorous vacuole. Here we revisit the existing literature that supports the presence of similar invasive behaviors in other apicomplexan parasites.
在疟原虫子孢子成功感染哺乳动物宿主的过程中，这似乎是一个必要的前奏，在此期间，疟原虫子孢子迅速穿过多个宿主细胞，并在此过程中突破细胞质膜。这种入侵模式先于“传统”模式，即子孢子通过宿主细胞膜内陷进入并在寄生泡内发育。在这里，我们重新审视了现有文献，这些文献支持其他顶复门寄生虫中存在类似的入侵行为。
