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本文引用的文献

1
Polymorphism of Neisseria meningitidis penA gene associated with reduced susceptibility to penicillin.脑膜炎奈瑟菌penA基因多态性与青霉素敏感性降低相关。
J Antimicrob Chemother. 2001 Mar;47(3):285-96. doi: 10.1093/jac/47.3.285.
2
Evaluation of the Applied Biosystems automated Taqman polymerase chain reaction system for the detection of meningococcal DNA.应用生物系统公司的自动化Taqman聚合酶链反应系统用于检测脑膜炎球菌DNA的评估。
FEMS Immunol Med Microbiol. 2000 Jun;28(2):173-9. doi: 10.1111/j.1574-695X.2000.tb01473.x.
3
Simultaneous approach for nonculture PCR-based identification and serogroup prediction of Neisseria meningitidis.基于非培养PCR的脑膜炎奈瑟菌鉴定及血清群预测同步方法
J Clin Microbiol. 2000 Feb;38(2):855-7. doi: 10.1128/JCM.38.2.855-857.2000.
4
PCR identification of the group A Neisseria meningitidis gene in cerebrospinal fluid.脑脊液中A群脑膜炎奈瑟菌基因的聚合酶链反应鉴定
Scand J Infect Dis. 1999;31(5):481-3. doi: 10.1080/00365549950164003.
5
The detection of penicillin insensitivity in Neisseria meningitidis by polymerase chain reaction.通过聚合酶链反应检测脑膜炎奈瑟菌对青霉素的不敏感性。
J Antimicrob Chemother. 1998 Sep;42(3):303-7. doi: 10.1093/jac/42.3.303.
6
Detection of bacteraemia in patients with fever and neutropenia using 16S rRNA gene amplification by polymerase chain reaction.采用聚合酶链反应通过16S rRNA基因扩增检测发热伴中性粒细胞减少患者的菌血症
Eur J Clin Microbiol Infect Dis. 1998 Apr;17(4):247-53. doi: 10.1007/BF01699981.
7
Amplification of the meningococcal porB gene for non-culture serotype characterization.用于非培养血清型鉴定的脑膜炎球菌porB基因扩增
Epidemiol Infect. 1998 Jun;120(3):257-62. doi: 10.1017/s0950268898008656.
8
Diagnosis of meningococcal meningitis by broad-range bacterial PCR with cerebrospinal fluid.采用脑脊液广谱细菌聚合酶链反应诊断脑膜炎球菌性脑膜炎。
J Clin Microbiol. 1998 Aug;36(8):2205-9. doi: 10.1128/JCM.36.8.2205-2209.1998.
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Characterization of the gene cassette required for biosynthesis of the (alpha1-->6)-linked N-acetyl-D-mannosamine-1-phosphate capsule of serogroup A Neisseria meningitidis.A群脑膜炎奈瑟菌（α1→6）连接的N-乙酰-D-甘露糖胺-1-磷酸荚膜生物合成所需基因盒的特征分析
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10
siaD PCR ELISA for confirmation and identification of serogroup Y and W135 meningococcal infections.用于确认和鉴定Y群和W135群脑膜炎球菌感染的siaD聚合酶链反应酶联免疫吸附测定
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脑膜炎奈瑟菌对青霉素敏感性的非培养法预测

Nonculture prediction of Neisseria meningitidis susceptibility to penicillin.

作者信息

Antignac A, Alonso J M, Taha M K

机构信息

Unité des Neisseria, Centre National de Référence des Méningocoques, Institut Pasteur, 75724 Paris Cedex 15, France.

出版信息

Antimicrob Agents Chemother. 2001 Dec;45(12):3625-8. doi: 10.1128/AAC.45.12.3625-3628.2001.

DOI:10.1128/AAC.45.12.3625-3628.2001
PMID:11709355
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC90884/
Abstract

We developed a nonculture method to predict the susceptibility of Neisseria meningitidis to penicillin G. The penA gene was amplified and submitted to restriction fragment length polymorphism analysis. This approach was first validated with a collection of 75 meningococcal strains of known phenotypes. It was next successfully applied to 29 clinical samples.

摘要

我们开发了一种非培养方法来预测脑膜炎奈瑟菌对青霉素G的敏感性。扩增penA基因并进行限制性片段长度多态性分析。该方法首先用75株已知表型的脑膜炎球菌菌株进行验证。接下来，它成功应用于29份临床样本。